I think the problem with the ethics in doing double blind trials with vaccines, is that it is considered highly unethical to knowingly expose a group of people that you know have no protection, to a potentially fatal disease. That is why there is no, and will never be, any double blind vaccine trials into diseases like polio, tetanus etc.
perhaps Little Chicken..but I think it would be easy enough to take a randomised group of children whose parents have made the choice to not vaccinate them, and compare their health to a randomised group of children whose parents have chosen to vaccinate (according to the prescribed schedule) in terms of:-
* incidences of communicable diseases
* long term health effects
* short term side effects
* rates of morbidity
* rates of autism and other learning disabilities and other disabilities
* rates of allergies and autoimmune illnesses etc etc etc etc
This is so obvious and should have been done a long time ago but theres about only two researchers I can think of that Im aware have started to do this.. one a homeopath in Australia, and the other was some researcher in Europe somewhere.. (somewhere like Germany).. Ive read that much I can't remember where Ive read things anymore...
One of the previous links posted for a double blind randomised controlled trial for pertussis looked at side effects but only in terms of redness and swelling at the injection site from what I can see in a quick read of the article.. I can't get access to the full article and can't be bothered searching for where I can right now as its late and I should be asleep!! But anyway.. its just typical of those sorts of studies - they are interested only in antibody response, swelling and redness, and they usually only monitor the children for about 24hrs post vaccination.. (not good enough for me to decide to inject my bub)...
As I said, there are hardly any studies anywhere that look at long term health effects. Why are we seeing all these modern day illnesses that never used to be around before vaccinations, e.g heart disease, cancer, increases in psychiatric illnesses and autoimmune diseases, adhd, autism, diabetes, irritable bowel syndrome,food allergies, and the list goes on.. . all modern day stuff.. whats causing it??? why does it seem to coincide with the introduction of vaccines?? (vaccines introduced approx 200yrs ago... and probably only in the last 3-4 generations these illnesses have increased). prior to that it was things like kidney failure, malnutrition, and deaths from communicable diseases (whether you believe that vaccination decreased those communicable diseases or those diseases reduced in the population for other reasons is a whole other kettle of fish which I can't be bothered getting into a debate about)....
And how is it considered ethical to vaccinate children with these substances if noone has looked fully into the health effects in the first place?? I think that ethics just go out the window when it comes to vaccines..