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i have had it twice, first time i had my periods for over 6 months second time i was told wait 5 years and test it again but same thing happened so i have NEVER taken it again. it did not agree with me at ALL!
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I was on depo provera for just over 3 years. I lost my libido, and 40kg.
I also suffered from depression whilst I was on the shot (but recently found out I am intollerant to wheat/yeast/gluten so that could have also been a trigger!).
I went straight from depo provera onto the pill, and have had a period every month on that (have not gone off the pill yet, as we don't want babies just yet!).
I have been off the depo provera for about 6 months now, and still don't really have my libido back.