Printable View
i used last pregnyl shot on the thurs, tested it out of my system by the sunday, started getting BFP's on the monday
i would suggest you test it out of your system - if you get a positive, take it with a grain of salt, test again next day - if it's darker, it's a good sign, lighter or gone, means the positive was from the pregnyl (does that make sense)
thanks bg. it's just so hard as i usually have a natural cycle and i want to do a test early but don't want to get a negative result. thanks again. will try the testing out theory.
I hope this is the right place to post; I have an IVF question.
I started puregon on Friday and will have a BT on Wednesday (after 5 injections), just wondering if anyone knows when EPU will be? I am supposed to go away the long weekend, but am thinking I should cancel?
Any ideas?
Hi sandygirl,
I had 12 days of puregon, one day with no drugs and next day EPU. So 14 days after I started the injections. I think it can also depend on how your follicles are looking. It can be a little earlier. You will definately find out on your next scan.
Hope it helped.
Sandygirl,
I had 10 days of Puregon, 1 day no Puregon then next day EPU. For me it was affected by the long weekend in WA so I had to have EPU on Friday. My clinic didn't get theatre time again until Wednesday so I couldn't hold off that long!
Depends on your clinic but you may have EPU on the Monday of the long weekend or a day or two after that. You'll also have to factor in taking your trigger shot ~36 hours before EPU (so if you don't have a trigger already make sure you get one from your clinic on Wednesday).
Thanks esperan and Mrs P, very helpful.
Roughly that would make BT wed, US Friday and probably another US on the weekend with trigger then too. I guess I will stay in sydney then. Either way I will find out the process on Wednesday. :pray: the puregon is working.
Hi there,
I had a Hyst & Lap performed today and found that my tubes are clear but they are adhered to my ovaries, meaning a natural BFP is unlikely. Not impossible - just really challenging.
My FP advised that IVF would be the way to go from here. My head was already spinning as I was in the recovery ward and now I just have so many questions.
I am eager to start as soon as possible but wondered if anyone could advise how long you are on the meds before you need to be going in for the blood tests and ultrasounds?
We have a holiday planned to NZ in early July which I would gladly cancel but perhaps there is no need if the monitoring hasn't begun?
Also, I am unsure how long after the hyst & lap they would wait before IVF?
I am brand new to BB so please let me know if I should be posting elsewhere!
TIA
Welcome to BB Taurean.
I hope you find all the support you need here.
I had a lap (for different reasons) prior to starting IVF.
My timeframes went bascially like this:
4 weeks after the lap: I had an appointment with FS.
(I had to have bts and U/S between 1st app and AF arriving.)
I week later: AF arrived.
(Then I had an app to get all the meds.)
At day 21: I started provera tablets.
Day 22: I started synarel spray to suppress hormones.
Next AF: arrived a week later. (1st monitoring BT was Day 4 of this cycle)
I am now on injections to stim the ovaries.
I hope this helps.
The first step is making an appointment with FS at the IVF clinic and going from there. The doc will get all your history and advise what is best. GL with your journey.
Thanks Sandygirl.
I have made an appt with the IVF clinic today to meet the nurse. The first available appt was for Fri 26th of June so I took it. Couldn't believe the wait - takes longer than it did to get into FS!
So I will go to FS on Mon 15th for post-op check-up and so she can devise her treatment plan for me.
My appt with the clinic is on Day 5 of my cycle so I think that times in well from what I can understand. With a bit of luck I am hopeful that we can have our first IVF cycle in July.
Thanks for spelling it out for me. All the best with your journey.
Hi everyone, just thought I might post this in here.. I am on CD11
do these dosage amts sound high?
Puregon 225iu everyday, orgalutran 0.5ml everyday and pregnal 0.1ml every second day.
When should I expect epu? and is it normal to have ewcm now?
Thanks!
Hi Krikket,
Sorry I can't help with the dosage but I had tonnes of EWCM during stimming.
Hi Krikkit,
I can't tell you about Orgalutran or Pregnyl as I have not had a stim cycle protocol using these drugs myself (other than Pregnyl for triggering ovulation) but I can tell you that the dose of Puregon you are on is a fairly normal dosage.
There is a real range of "normal" in terms of dosage for FSH, and it completely depends on the individual and things like your weight, how sensitive your FS thinks you may be to responding and even your previous response to the drug if you've had a previous cycle etc. but in my first IVF cycle I was on 225 like you (except I was on Gonal-F instead of Puregon). I know that 225 would be a higher dose for some women but not necessarily for others - in my next cycle my dosage went up to 262.5.
I would think it's normal to have EWCM at CD11, especially if it is more than you are used to as your other cycle hormones are being triggered much more than normal when you are on Puregon - I used to like to think I was having a "super cycle".
EPU will depend on how your follicles are developing and how your oestrogen levels are doing. You'll be advised when it will be with a couple of days notice, when you are told to take your trigger injection. I don't know whether you have a normal cycle when you're not doing an IVF stim cycle, but I found that my EPU was always a little bit later than my normal ovulation time, which CD15 for me. It'll certainly be around the CD14 time, but could be a bit later by a number of days - all depends on your response.
HTH, and much good luck with your cycle! Fingers crossed for lots of good mature eggs! :pray:
Miss C
miss c- you are a tower of knowledge ;)
Since my surgery 3 weeks ago today, I have still not had AF turn up. I am on day 32 and my longest cycle prior to this was 30 days - averaging 28. Is it normal for these kinds of procedures to muck up your cycle? I bled for about 4 days after the surgery from the hyst.:
I have PMS - big time crankiness :pms:and lovely chin zits but nothing to match it!!!! For once I want it to turn up and be done with it. Any advice appreciated
Hi there,
Bit new to posting, so hopefully someone reads this. I just got a negative blood test at 19 days post-IUI (#2). It's just odd, because I still haven't started my period, and I've never been this late. I did have Pregnyl (1500) on days 4 and 8 (post IUI). But last cycle, I got my period bang on 15 days post-IUI, with the same protocol.
I just have no idea when my next cycle will start now. Has anyone else had their cycle delayed and by how much? The nurse was very non-specific, like "just wait". It's not very comforting. Any advice?
Hi Worrywart, Unfortunately your nurse is probably correct - you do have to "just wait". the hormones impact everyone's bodies to a different extent and things can vary with one person from one cycle to the next, so really no-one can predict when Af will arrive. Were you having progesterone as well? that can often delay AF.
Hi Anney,
Thanks so much for your reply. I'm sure you're right. I've never had a really delayed AF (even on clomid) so this is a new experience for me. Nope, I wasn't on progesterone. Sometimes it's tempting to speculate on "Why?" etc but I guess I am just looking forward to the start date of a new cycle.
Anyway, thanks again and best of luck for your own treatments.
I am not sure where exactly this post belongs, so i will try here and hopefully not offend anyone. I was wondering, for those going through ivf second time round, are you allowed to BF whilst doing a FET?? I am thinking not, but have a FS appt in a couple weeks. If the FET doesnt work then we will wait for another 18 months or so before doing a full cycle again and it will be disappointing to stop BF'ing.
Thanks :) Mel
Everything I have seen, read and heard is a resounding no. The drugs used in FET cycles aren't safe while breastfeeding. Even if you are having natural cycles, they believe that the BF hormones will act against implantation.
BW
Thanks BW. Pretty much thought so. I wonder how long i will have to stop BF'ing for before the t/f. Lots of questions to ask FS. Poor DS he loves his booba!
Double Posting
Hi,
I have a couple question regarding NK Cell test and what the results mean.
Question No 1: Total NK Cells (CD3- 56+), What percentage level is classed as normal.
On My sisters test result her level was 19.8% and they said that was classed as Very Very High levels. She requires Prednisilone and Clexane for her future IVF cycles.
Question No. 2: On my results for the NK Test there was hand writing on my test from lab regarding, Activited (CD69+) dim NK’S, does anyone know anything about this?
A lot of the NK tests do not have this information written on it as it is only done if your doctor specifically requests it and if they specialises in immunology.
Mine reads as Activited (CD69+) dim NK’S = 2-1% = 4.2 x 10 6/L
Does anyone know what percentage this should be and what percentage rate is considered as high and low.
Quote:
Originally Posted by Inanna View Post
The NK cell is the most abundant immune cell infiltrating the womb implantation site. In a previous study, an elevated percentage of peripheral blood NK cells were associated with recurrent failed IVF-ET treatment cycles. Another study showed that increased peripheral blood NK cell toxicity was associated with an increased rate of recurrent failed implantation after IVF-ET treatment. More recent studies have confirmed elevated NK cell CD69 expression as being associated with recurrent miscarriage and infertility of unknown reason.
I also found this on a UK site: But I don’t know if there tests are done differently to ours:
• The NK cell is the most abundant immune cell infiltrating the womb implantation site. In a previous study, an elevated percentage of peripheral blood NK cells were associated with recurrent failed IVF-ET treatment cycles. Another study showed that increased peripheral blood NK cell toxicity was associated with an increased rate of recurrent failed implantation after IVF-ET treatment. More recent studies have confirmed elevated NK cell CD69 expression as being associated with recurrent miscarriage and infertility of unknown aetiology. Finally, a recent small non-randomised study has also suggested elevated NK cell CD69 expression may be related to failed implantation of the embryo.
We also recently conducted a study to evaluate the effect of the absolute count of the activation marker (CD69) and inhibitor marker (CD94) expression on peripheral blood NK cells on implantation and miscarriage rates after IVF-ET treatment. It was a randomised prospective observation study of 138 randomly selected women who underwent IVF-ET treatment from December 2002 to September 2003. Our data suggests that an elevated level of CD69+ peripheral blood NK cells is a detrimental factor for implantation of embryos in IVF-ET treatment. Those women who have an elevated peripheral blood CD69+ NK cell count achieve a positive pregnancy from IVF-ET have a significantly higher risk of miscarriage. The specificity and positive predictive value of predicting IVF-ET outcome for women who have a peripheral CD69+ NK cell count above 1.0 x10 6 /L are 92.1% and 92.3% respectively. This test may therefore be used in clinical practice to predict negative outcome of IVF-ET treatment.
Any information is greatly appreciated.
Just saw this - I actually found a study that found that it is not necessary to wean completely if you have regular, natural cycles. FS's will disagree most likely.: