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Monozygotic or identical twins occur when a single fertilized ovum divides into two physically separate, but genetically (almost) identical embryos. The single fertilized ovum divides very early in gestation, usually within 8 days after conception. Monozygotic twins, having a very similar genetic make-up, are always the same sex, have the same blood type, and usually look very similar. However, there are exceptions and some monozygotic twins do not have EXACTLY the same genetic composition.
Dizygotic or fraternal twins arise from multiple ovulation. Normally, just a single ovum is released from an ovary each month. When more than a single ovum is released it is called multiple ovulation. If all of the ova are fertilized, genetically dissimilar twins (or higher multiples) occur. Dizygotic twins usually share no more similarities than would be expected with any siblings. They often have different gender, blood type and other characteristics.
There are several clues as to whether the twins are identical or fraternal. If they have a different gender or blood type one immediately knows that they are fraternal. At the time of delivery, the doctor can examine the placenta. The membranes that surround the babies before birth often have a characteristic pattern with identical twins. However, this method is not certain in all cases. In some cases only genetic testing can tell for sure if twins are identical.
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