MTHFR mutation

We have the MTHFR mutation in our family and have had great results through supplementing methylated B vitamins. Feel free to chat here :)

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I know you've removed this but for anyone curious: MTHFR - Is The MTHFR Gene Mutation Affecting Your Pregnancy?

This is something I ventured in here for to ask about.

I was told I had this gene mutation prior to the birth of my first child.

The doctor gave me a super dose of Folic Acid (Megafol) and I took this during the length of my pregnancy.
I was told that it was believed that this mutation had something to do with my previous miscarriages and lo and behold I had a trouble free pregnancies and healthy babies. Not too sure if that had anything to do with it but I had a string of miscarriages and then, bang, two successful ones in quick succession.

Thing is, I read in the article that those found to have this mutation should stop taking folic acid immediately. However, other articles of this ilk found elsewhere do not state this.

Am I missing something?

Thanks.

I have read that folic acid is not good and you should be having a methylated form such as folinic acid. But if it worked for you then why worry huh?

That's not really helpful. Do you have the gene mutation?
There's plenty to worry about at my age and with my history and thought someone in here might have trodden the same path that could have shed some light on it, that's all.

I'll see the community nurse today and ask.

VM: that article was written by a leading authority - a specialist in MTHFR. I'd get the form he suggests and stop folic acid.

I have compound heterozygous MTHFR. I do not take folic acid at all, as I do not absorb it. I take methylated folate. If you google Ben Lynch (the author of the above article), you'll find a site with a lot of information on it. Most health providers don't really understand it, as it is quite common in the population and not really considered a problem.

I find that when people are trying to be helpful, someone telling them they're not being helpful because the information given isn't what they wanted or expected, can be perceived as extremely rude.

You have two children after having miscarriages so I'm not sure what you are concerned about? Perhaps if you could clarify your concern we could help. Do you feel you may have caused your children health problems by taking folic acid in your pregnancies?

Hi BellyBelly, I did read the article and went to his site to read up on it prior to posting. The reason I posted my query was because I'd read other experts regarding this issue which suggested differently so I was wondering if I was missing something. I printed out the article and brought it with me to my assessment. The specialist, in turn, directed me to additional literature which helped me put everything into perspective. I did not realise that there is still so little known about this mutation and yet it appears to be so common.

The upshot of it is that I am homozygous C677T. I have been placed on MegaFol, MegaB and low dose aspirin until birth. I'm relieved that my concerns were taken seriously and that I am now on a definitive plan that will maximise bub's chances of a healthy outcome.

Lions, I find that a one line retort that dismisses and therefore invalidates the concerns of the questioner is very rude and quite puerile really. However, I did not mention my findings in this regard as I did not feel that this would be helpful either. Instead, I responded with an honest, polite and straightforward reply I believe sets a tone appropriate to issues such as this. I found that others saw it as I did which was helpful :)

Thank you to those that responded kindly. I appreciate your time.

I'm also compound heterozygous for MTHFR and have known for 6 months but have just started seeking support and researching a couple of weeks ago.
From my wide reading, folic acid is RUBBISH!
There's no excuse for any of us to be taking this synthetic form as those with MTHFR defects (estimated at least 20% of the Australian population) get sicker with it.
I don't get why women and especially those TTC are given folic acid when it can contribute to miscarriages and numerous other issues.
Folinic acid is much better to take for the general population and methyfolate for people with MTHFR genetic defects.
Most GP's haven't done the training to understated this defect and it affects everything from mental health, some cancers, pain, weight, brain fog to fibromyalgia and heart disease.
There are numerous websites with loads of info but the one I read the most is Dr Ben Lynch who's is an expert in this field.
I recommend everyone gets tested. Xx

I'm pretty sure they tell you to take folic acid because the research is very clear that it reduces the incidence of Spina bifida, and it's the only supplement that has been clearly shown in research evidence to prevent a disability.

But I agree with learning more about individual circumstances and getting tested for everything you can if you're TTC and especially if you're LTTTC. It must be frustrating having only recently heard about it.

Absolutely myturn. It has shown to help a section of the community however, for the rest of us, it is a major factor in miscarriages, mental health issues, chronic fatigue, insomnia to name a few. The more natural form of folate ( Folinic acid) is a much more widely tolerated by as far as I know in the whole population.
I think being tested for the MTHFR genetic defect/ mutation should be part of a regular full blood test.