misscarriage and pcos

hi there evryone, my name is kelly and I am new to this forum :D . Just wandering if anyone with pcos have had any misscarriages while taking serophene or clomid. I was on serophene for the first time and fell pregnant and on the same day I found out I had a miscarriage, I was then told to wait a few months before going back onto the tablet. Nothing happened for the next few cycles so i was then put up to 100mg and i fell pregnant again, then 6-7 weeks into my pregnancy i miscarried again. I am now on clomid and i am terrified of miscarring again. I am beginning to wonder if i will ever fall prenant 8-[ .has anyone had similar story, i would love to hear from you, as i fell very alone. :help:

Kelly
Hi, firstly may I say I am so sorry for your losses. I have previously done 4 cycles of clomis and I unfrotunately did not get pg. I did however last cycle (FSH injectoins and AI) get pg only to miscarry at 8 weeks.
Having PCOS we are more prone to m/c.
Also as my Dr has always told me ovulation induction may bring out eggs that ordinarily would not have matured so they may not be intended to be viable.
Hope this makes sense.
I look forward to getting to know you and wish u all the best with your journey.

Thankyou for reply shezabelle, what you said did make sense, I only wish things were easier. :D

Ditto to that!!

Hi moonlight, sorry to hear of your trouble. I personally haven't managed to fall pregnant with PCOS. Hopefully your turn is coming. :)

Hopefully someone with more experience than I can offer some words which can help

Hi,
Sorry for your losses. I hope you get a good result soon!
Shezabelle, can you explain why PCOS sufferers are more prone to miscarry? I figure it has to do with the hormones being out of whack - but is it something more specific? Its looking like I have miscarried myself - confirmation bt on Monday. I guess I'm searching for answers.
Thanks
blue

Hi moonlight,

Apparently PCOS women are more prone to miscarriage. Sorry to hear of your disappointments :(

My OB started me on Metformin and I'll be on it to the end of my first trimester. The plan was to go onto clomid, but I didn't end up needing it. But apparently Metformin helps you to respond to the Clomid, and remaining on it for the 12 weeks helps reduce miscarriage. Perhaps you could talk to your specialist about Metformin. It is still a controversial drug with regards to staying on it while pregnant, as there aren't any extensive or conclusive studies that can categorise it's safety. However, I trust my OB and he's kept me on it. This is my first pg, and I'm hoping it'll stick.. going well so far :) I was a little worried, coz my mum had 3 miscarriages herself.

I hope you're able to find a solution soon, and your next one will stick!

blue - sorry to hear that it's possible you've miscarried. All the best.

:pinkstick: :bluestick: for everyone :)

Blue.. I was under the impression that PCOS sufferers were more prone to miscarraige due to the hormone problems but I actually found out last week from my DR that latest studies show there is no increase in incidence.
Whether the lengths we need to go to to get pg have a bearing on perseved numbers is another story ie as I said in an earlier post the eggs that are brought up through stimulatation may not have been intended to do so.
I really hope monday brings good news but know that if it doesn't we are here for you xox

Thanks Shezabelle,
Unfortunately the numbers have dropped even further. Looks like it just wasn't my time.
cheers
blue

Hun, just wanted to let you know that Im so sorry for your losses.

It will happen for you darlin'. O:)

Sorry to hear of you losses - i too am a PCOS sufferer and have Endo thrown in for good measure... The first round of clomid we fell pg straight away and couldn't believe our luck only to lose it a week and a bit later. I was to let my body recover but after eight weeks of no AF after the m/c they induced a bleed, second round of clomid failed and now finally we are round three and have upped the dosage. I can sympathise with how you are feeling i worry about it but try not to think about it now...i hope that this is a good cycle for you and it is a success...

oh hon - I am sorry for you losses :( I too have PCOS and had 2 miscarriages late in the trimester. They weren't clomid pregnancies but the third pregnancy I had was clomid. I conceived twins and we lost a twin at almost 10 weeks. My next pregnancy was clomid and that went to term.

I wouldn't imagine clomid would be the results of your mc. But what my doc did with my last pregancy was moniter my progesterone levels weekly as PCOS women can have a progesterone issue and progesterone support might be necessary until the placenta takes over. Thankfully I didn't it but it would have been nice to know with my first pregnancies :(

All the best

My first pregnancy I wasn't on progesterone pessaries and had repeative bleeding at 5,7,9,12,14 weeks finally my membranes gave way at 16 weeks either due to the bleeds or IC,
My second pregnancy I was on Progesterone 2 a day and had no bleeding but my membranes gave way at 20 weeks due to IC.
3 rd Pregnancy on progesterone and was stitched at 13 weeks to prevent IC.
There has been studies done on progesterone support and PCOS, my obst would not let me off them till 14 weeks.
There has also been an increasing amount of women with PCOS and Incompetant Cervix's which there is currently a study being done. It takes so long to fall pregnant at least cover all bases and discuss it with your treating doctor, and a boodtest doesn't hurt nor does an ultrasound
Good Luck
Bec

Hi Guys,
I have well advanced PCOS and am absolutely terrified of miscarriage im currently 16 weeks pregnant and my dr took me off the metformin as soon as we found out about the baby. Peanut wasnt planned but still managed to be, was a very big surprise.
To those of you who have PCOS and havnt been able to conceive or have had miscarriages my heart goes out to you it really does. I have lived with PCOS since i was 11 years old and have all the tell tale signs and symptoms (excess weight gain, excess hair growth, bad mood swings, odd periods, you name it) if anyone wants a shoulder or someone to talk to who has lived with PCOS for a very long time gimme a yell im always available for a chat. Some times the best person to talk to is someone outside your normal circle.
Have a great day
Mel :D

Mel - congrats on your special surprise :D I'll be keeping my fingers and toes crossed that you have a sticky bub :pinkstick: :bluestick:

Hi,
I have just found out I am pregnant , however I am petrified of m/c... This is our first and i am almost making myself sick with worry... I have bad stomach cramps (like period pain) and i am convinced its not going to work out...
You hear so many sad endings... is there any chance of going full time with PCOS with your first....
My husband is so excited but i am just to worried to be excited...

Rachxox [-o<

Rach,
Congratulations first off..I remember talking to you in another thread re your doctor who was the same as mine! Progesterone is a really important issue for the first 12 weeks of pregnancy in PCOS. I will PM some information. Try and relax and enjoy the miracle that you have inside.
Bec

Hi everyone,

I also have PCOS and have just concieved my first. Keeping my legs crossed so it stays in :lol:

My endocrinologist showed me the results of a study done on women with PCOS. Staying on metformin for the first 12 weeks reduced the chance of miscarriage by 50%. SO I'm definitely staying on it. He didn't exaplin the reason, but I trust him on this :D

Kylie