pregnancy and clexane

Hi everyone

happy i found this site as it has helped me relaxe already.. i had a miscarriage at 17 weeks +5 days. after loads of blood test i was told i had antiphospholipid. ( sticky blood syndrome. i am now 7 weeks pregnant and i have been taking baby asprin, and clexane 40.mg daily. im very scared as im still early, i have been having scans every two weeks, 1st scan went fine and i see the tiny bump. very scared for next scan which is due on monday. i should see the heartbeat so fingers crossed..

would love to hear from people who are experiencing the same thing or have been throught a miscarriage as im new to the site......x:D

Hi Bailey

sorry to hear about your loss - did u know about your APS before your last pregnancy?

I also have APS - i was diagnosed in 2006.. i lost my baby girl on last week at 21 weeks and 4 days... from what i understand i have quiet sticky blood and so was put on 100mg clexane daily - no asprin...

up until 14 weeks my scans looked great and the OB was really pleased.. at my 19 week scan i was told that the baby was small for he age - 3 weeks behind in growth.. at my 20 week appt with the OB i was told that there was very little fluid surrounding her and that it was very unlikely that she would survive.. this was my first pregnancy..

when i was in hospital last week i met a haem who told me there is some merit in taking clexane twice daily and also taking the asprin.. so he was suggesting that would take 3/4s of the dose in the morning and then again in the evening.. talk to your OB/haem about this..

i have also heard that there is some benefit in taking fish oil supplements during pregnancy - i am yet to ask my specialist about this as i have only just found out about it..

not sure if you have been told but you should be taking calcuim plus vitamin d as clexane messes with your bones...

apart from that drink plenty of fluid - probably the one thing i didnt do enough of

all my fingers and toes are crossed for you and i hope you had a good scan!

L

Hi Bailey0808.
Thought I was the only pregnant person on clexane at the moment. It is very rare from wat the docs tell me. I also take low dose asprin everyday as well as injections 40mg.This is my 4th pregnancy (13wks) & the two before were on clexane but not with first as was"nt aware had leidan factor 5 (blood clotting) until my 3rd miscarriage 10yrs ago. I was 14.5 weeks with that one & feel 4 u losing at that later stage. On a brighter note I think u will be fine. Scary I know but as Ive had the last 2 fine im not as worried bout this 1. Hope this eases your mind a bit & congratulations & good luck.
Anna..

Hi and congrats on your pregnancy!!
I too am on clexane, but for a different reason. I had a large blood clot in my first pregnancy so I take it as a preventative. I had it in my last pregnancy and my DS was fine. I hope it all works out well for you and good luck with you're next scan, I hope you hear the heart beat :)

Hi Bailey

How did your scan go - my fingers were croseed for you..

LB

Hello

Im 17weeks + 1day and also on Clexane 40mg a day. Late last year my daughter Peyton was stillborn at 38+ weeks I was later told i also had APS. I also take Asprin everyday and to add to the stress was told at 6 weeks i have Gest Diabetes, which was a total suprise due to my age,race and weight, so also inject insulin 3 times a day.
Im still getting used to these fat Clexane needles that even after a few mths i still manage to hit a vein and bleed now and then.
I have my 3rd U/sound next week and will hopefully find out if baby is a boy or girl, then every 3-4 weeks till im about 30weeks then every 2 weeks to make sure baby is getting enough blood etc. Doctors are looking at inducing me before i hit the 38 week mark again.
I also have Auto Immune sickness but that didnt come on till after the birht of my 2nd child 9 years ago.

Good Luck with your Clexane and baby!!!!

:

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Hello

Im 17weeks + 1day and also on Clexane 40mg a day. Late last year my daughter Peyton was stillborn at 38+ weeks I was later told i also had APS. I also take Asprin everyday and to add to the stress was told at 6 weeks i have Gest Diabetes, which was a total suprise due to my age,race and weight, so also inject insulin 3 times a day.
Im still getting used to these fat Clexane needles that even after a few mths i still manage to hit a vein and bleed now and then.
I have my 3rd U/sound next week and will hopefully find out if baby is a boy or girl, then every 3-4 weeks till im about 30weeks then every 2 weeks to make sure baby is getting enough blood etc. Doctors are looking at inducing me before i hit the 38 week mark again.
I also have Auto Immune sickness but that didnt come on till after the birht of my 2nd child 9 years ago.

Good Luck with your Clexane and baby!!!!

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hi thank you for your reply so sorry to hear about your loss at such a late stage.. its so nice to see other people going through the same thing as me as i was beginning to think i was the only one. yeah im just starting to get used to the injections although mine are quite slim?? it's good to hear your getting lots of scans to put your mind at rest. good luck on your next scan, hope all goes well for u, what are u hoping for (boy/girl)...xxxxx

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Hi Bailey0808.
Thought I was the only pregnant person on clexane at the moment. It is very rare from wat the docs tell me. I also take low dose asprin everyday as well as injections 40mg.This is my 4th pregnancy (13wks) & the two before were on clexane but not with first as was"nt aware had leidan factor 5 (blood clotting) until my 3rd miscarriage 10yrs ago. I was 14.5 weeks with that one & feel 4 u losing at that later stage. On a brighter note I think u will be fine. Scary I know but as Ive had the last 2 fine im not as worried bout this 1. Hope this eases your mind a bit & congratulations & good luck.
Anna..

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hi ya
yeah i thought the same thing, been searching for ages to find people..
so sorry to hear of your misscarriages. thank you has i haven't till now found anyone whos been using clexane and had a fine pregnancy. even though docs tell me theres loads. i hope all goes well with u and ur baby.xx

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Hi and congrats on your pregnancy!!
I too am on clexane, but for a different reason. I had a large blood clot in my first pregnancy so I take it as a preventative. I had it in my last pregnancy and my DS was fine. I hope it all works out well for you and good luck with you're next scan, I hope you hear the heart beat :)

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thenk u..x
where did u have the blood clot and was u told what had caused it?? had the scan and all was well:D

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Hi Bailey

How did your scan go - my fingers were croseed for you..

LB

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thank you:D
all was well see baby and heart beat so things are looking good at the moment, still a bit scared to get really positive but im still smiling...x

hi all,

i posted a long reply with my experience but clearly did something wrong..

i have APS too.. i was pregnant for the first time this year and my baby girl was born sleeping at 21 and a half weeks on the 5th August..

i have heard of people on clexane that have delivered healthy babies bailey so dont worry :)

my pregnancy was going well until i had a 19 week scan where the sonographer told me she was measuring small for the age.. knowing what i know now - next time i will be looking for this right away.. i have been transfered into the care of a sub-specialist for next time..

two things i have learned following my expereince..
clexane doses are given according to weight so as you progress in your pregnancy there may be reason to increase your dose - i wasnt on asprin and thats what a heamatologist at the hospital told me - so i would be asking your heam..

and secondly - fish oil supplements - see this site - again i'd be asking the medical people... Fish Oil Derivatives as a Prophylaxis of Recurrent Miscarriage Associated with Antiphospholipid Antibodies (APL) : a Pilot Study -- Rossi and Costa 2 (5): 319 -- Lupus

i have been taking them since moving back onto warfarin and its making a big difference to my INR and daily warfarin doses.. i've always been on 12mg (since 2005) and now im down to 10mg (hoping to go lower)..

my fingers are crossed for you all...

i see the specialist in a months time and i plan on TTC again once AF returns.. so will let you know if i learn anything insightful

LB
x

hi again..

i've found another article - unfortunately i can only read the abstacts - i might have to head to the uni library and find the articles in full once i've got a list.. but the results are state on the abstracts.. is quiet promising for APS people..

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hi all,


i have APS too.. i was pregnant for the first time this year and my baby girl was born sleeping at 21 and a half weeks on the 5th August..

i have heard of people on clexane that have delivered healthy babies bailey so dont worry :)

my pregnancy was going well until i had a 19 week scan where the sonographer told me she was measuring small for the age.. knowing what i know now - next time i will be looking for this right away.. i have been transfered into the care of a sub-specialist for next time..

two things i have learned following my expereince..
clexane doses are given according to weight so as you progress in your pregnancy there may be reason to increase your dose - i wasnt on asprin and thats what a heamatologist at the hospital told me - so i would be asking your heam..

and secondly - fish oil supplements - see this site - again i'd be asking the medical people... Fish Oil Derivatives as a Prophylaxis of Recurrent Miscarriage Associated with Antiphospholipid Antibodies (APL) : a Pilot Study -- Rossi and Costa 2 (5): 319 -- Lupus

i have been taking them since moving back onto warfarin and its making a big difference to my INR and daily warfarin doses.. i've always been on 12mg (since 2005) and now im down to 10mg (hoping to go lower)..

my fingers are crossed for you all...

i see the specialist in a months time and i plan on TTC again once AF returns.. so will let you know if i learn anything insightful

LB
x

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hi lanabear81
so sorry to hear about your loss, i hope ur staying strong and looking to the future. so was u on clexane when u was pregnant or has it only been given to u now for ur next pregnancy. i was told the injections are the most important thing to take to stop any bloodclots forming in my placenta (has that was the reason for my loss) and the asprin is just another blood thiner to help benifit the baby?? goodluck with TTC:)

Hi there,
I too have anti phospholipid syndrome and had it diagnosed 10 years ago after I had a stroke. I had 2 miscarriages prior to the suscessful arrival of my son who has just turned 3 and have just now learned I am pregnant again. With my first successful pregnancy (my georgeous sons's pregnancy that is)I was on 2 daily injections of clexane as per the instructions of my wonderful doctor who is a specalist in medical disorders of pregnancy. Her theory is that twice daily injections stops the natural peaks and dips of the clexane metabolism by the body and maintains a more steady anti clotting defence. I was also on low dose aspirin.

I believe that anti phospholipid syndrome or lupus anticougulant as it is also known aslo has a high association with foetuses that are smaller in size than agarage and that regular scans should be performed to keep an eye on the babys growth. My son was born at 36+3 gestation weighing only 2.16kg or 4 ponds 8ounces so he was a little one but very healthy. Hope this helps and gives you a positive on the situation. All the best in your pregnancy!

Hi Everyone,
I was just looking on the net tonight about clexane and pregnancy and come across this site, and I have found it really helpful with all the comments that have been posted.

Im now 12 weeks and Im on clexane, I inject 100mg morning and night and have been for the last 7 weeks, I have been told by my doctors that I will be doing this all the way thru my pregnancy and for at least 6 weeks after birth.

I have DVT's (Blood Clots) in my thigh and at the back of my knee and only 2 weeks ago some of my blood clot broke off and travelled to my lungs so now I have clots on my lungs, that is why my dosage of clexane is so high.

Thank you all so much for your comments about the clexane subject and I hope to hear more stories for what I will look forward to later in my pregnancy.

Moonshine-

I took clexane after 2 very late losses due to IUGR. I was told that I most likely have a clotting issue but they are not able to determine which one. I took a much much lower dose than you and I had a big healthy son in June!

Hello,
I was on heparin injections for the first 20wks of our IVF pg, and then was just monitored. I was diagnosed with APLS but as I had only tested positive to ANA, and not the anti lupus antibodies, it was felt that once it looked like all was going well with the pg, that I could stop. Having said that I had very regular scans to check on growth, and stayed on asprin the whole pg. I then had clexane injections post the emergency c-section for another 2 wks just to make sure there was no clotting.

DS was born at 2.8kg at 37wks 4 days - a bit on the little side which we were execting as he was always a little small.

Wishing you all the best moonshine for a healthy baby - it sounds like you are getting great care.
FG

Hi

i'm on clexane and aspirin for this pregnancy too, after losing a couple in the second trimester. I've heard so many, many good stories about clexane and recurrent miscarriage: there are also lots of clinical trials demonstrating that even for *idiopathic* recurrent miscarriage (ie you don't have APS or an incompetent cervix or something obvious like that) that clexane can give you about a 70% chance for a baby next pregnancy. that's pretty good considering people who have never had a miscarriage fare only slightly better than that. clexane may have immunomodulating effects as well as anticoagulant effects - that's good too if you suspect your immune system may be at fault. everyone hates the bruises that clexane gives you but it's worth it in the end. also, you will get used to the needles - the first few weeks it seems surreal but then it gets easier