I've always taken mine in the mornings for all the reasons stated above... worked well so far.

Also my 12yo DD had the Gardasil immunisation last week... there was a bit of hysteria with girl's crying beforehand, screaming during the injection and trying to escape etc but no negative physical reactions. My DD told me they were all carying on a bit and that she wanted to tell them to 'get a grip' but she admitted that it was painful.

It was a really tough decision to make as well... but so far so good.