I'm about to drive 6 hours this weekend with DD to visit my parents. Have done the trip by myself, but not by myself with DD so dunno how it's going to go! If you stop every couple of hours and let him run around he shouldn't be too bad. Take along some kiddy CD's that you can both sing along to and some snacks, maybe a couple of special toys he can play with. good luck! Oh and don't forget the driving lollies/chocolate for yourself