Mother Goose has the right idea. I put the tip of the syringe just in the corner of DD's mouth and administer it in small squirts. I stumbled onto one thing with her though and we have no problems now as I asked her to see if she could suck it out of the syringe lol she loves watching the plunger bit go down and we used to practice with water and juice so she understands that it's not always an unpleasant experience. Now when she has to have medicine even if it's just panadol I measure it out and hand her the syringe and she pushes the plunger down herself-Little Miss Independence