She needs to take as much of the dose as possible, although smaller doses should be effective, it isn't the full treatment. I know what it's like - we usually use a 5ml syringe, pin DS down force him to open his mouth and inject it in then not let him move until he swallowed. After two goes of that he then found it a game so took his medication really well - although we still have to pin him down, he asks us to do that for antibiotics. Haven't had them for a while, fingers crossed he won't remember should he need them again.