WTH, we were once tossing around the idea of using PGD as we'd had three embryo transfers as part of our IVF treatment, three pregnancies and three miscarriages. Our FS actually advised against using PGD as he didn't think the extra expense was worth it and it couldn't test for all abnormalities... However, we don't have a history of trisomies like you do. I wish you every success in your treatment and hope that they manage to find the answers to the questions you have.

My story is a bit more like Baby Dreamtime's... Our first two stim cycles resulted in quite nasty OHSS. I ended up in hospital for a week and off work for a month with one of them, which was I think the milder case than the other where I stubbornly refused to go to hospital and toughed it out at home. We did not transfer those cycles, but sent all embryos to the freezer. However, we had crap thaw rates. From those two cycles we had a total of 52 eggs collected, a total of 11 blastocyst embryos, and only 3 of those embryos survived the thaw process. We have one other that may have, but I honestly believe it didn't (complicated story). All three embryos resulted in a pregnancy from those FET cycles, and all three embryos were miscarried. For our third stim cycle, I followed an extremely strict low-carb, low-GI, high-protein diet. I eliminated all junk from my diet, especially sugar... and it made the difference! We had our first fresh transfer! We had lower egg numbers (a relief!), and rather poor fertilisation rates as they took me to EPU slightly early to fully ensure that we avoided OHSS... We didn't avoid it completely, it developed with a positive pregnancy test and I'm now 21 weeks pregnant. Sorry for the ramble, I did just want to encourage you that the diet changes may be hell, but they are VERY worthwhile and I fully believe that they made all the difference for us.

BW