Anyone with severe male factor infertlity had success?

[stargazer]

[SIZE="3"]Hi All,
My DH (33, me:30) has severe oligospermia due to y-chromosome microdeletions. We are starting our 8th ICSI cycle and are running out of steam. I have had the whole gamut of tests and scans & they can find nothing wrong with me, so it seems that is the only issue. . I know that the y chromosome deletions are very rare and as such i havent heard much about success rates etc. Drs always sidestep that one - and start talking about donors as a backup. I would love to know if anone out there has had a similar experience and had success or knows of someone who has.
Cheers [/SIZE]

[Sara69]

Hi Stargazer,

Can't really help much but my partner has issues with DNA fragmentation - there are things that can be done such as vitamins (Menevit) and surgical sperm extraction. I think you should seek answers from your doctor, it can't be right going through so many cycles without moreinformaiton. I am not sure where you are located - we've seen Dr Lok at SIVF fro a 2nd opinion who is a specilist for male factor infertility. Wishing you good luck on your journey.

Sara

[stargazer]

Hi Sara
thanks - best of luck to you also! Im an in Perth & have just started at Hollywood (owned by SIVF).
We have tried Menevit but there was no improvement in DH's sample after 4 months so arent on it anymore. We have changed Drs a few times - never really felt like we have the right one. We know our problem is very severe, so i suppose we are a challenging case... I dont know what it is like over east, but Drs here are generally very busy and ours have taken upto 5 months to get an appt so i rarely see them and try to get the clinic to communicate with them & relay info back to me.
Hopefully Hollywood will have a different approach & it will work out better for us this time!

[Muppity]

Hi Stargazer

Firstly, , sounds like you need some

I think that I would be making an appointment with your current FS at their rooms (you should only have to wait a little while as a current patient) and go in with a list of questions that you want answers to. And don't leave until you are satisfied.

Also, you could possibly ask about PICSI which is something that SIVF are trialing (so the people at Hollywood should know about it) which helps them pick better sperm in the ICSI process.

Good luck

[stargazer]

Hey Muppity
thanks for your encouragement, back! I will make an appt - by the time i get in we should have had 1 or 2 more cycles which will be our limit trying with both our cells. After that we will consider donor although are not keen. As Hollywood doesnt permit donor unless they are family or a friend, we will have to look elsewhere, prob go back to our old clinic as they have a donor register.
I will look up PICSI on the net to find out more about it - thanks for the tip!
xx S

[Sara69]

Hi Stargazer just want to add to PICSI - we have used that as well and in the cycles we used it we had a better result than with the surgical sperm extraction.

Sara