Hi Julie,
OMG, how frustrating, and how dissapointing to have this information there all this time. This is the same genetic issue that I eventually tested postive for, for both mutations of the gene, have you Googled MTHFR?

From what I understand having this gene mutation means that your body does not absorb folic acid (B9) and B6 and B12 also. It is also supposed to result in high homocystein levels, which is linked to blood clotting. The MTHFR falls under the thrombophilia blood clotting disorder and can lead to/is linked to blood clots, stroke, heart attacks, altzeimers etc

MODS, I hope it is ok to post this link: MTHFR

See this para, very interesting: Because of a mother with MTHFR’s inability to efficiently metabolize folic acid and vitamin B9, the disorder has been linked to a variety of pregnancy complications such as chromosomal abnormalities, such as Down syndrome, and congenital malformations.

My FS immediately prescribe the following:
Low dose aspirin (like Cartia - 100mg I think) daily for life, regardless of TTC or not
Mega folate (5mg) daily for life - you can get this behind the counter at the chemist, it is actually cheaper than buying a 500mcg folate tablet
Clexane injections to thin the blood - I am on 20 mg/.20ml per day (my FS initially suggested starting from BFP. As I had never achieved before, I pushed for from ET, but still felt that it might have been too late, so my successful cycle I started the night of EPU).

I did get my homocystein levels checked and they were within normal range, however my FS felt that my ability to get to BFP was still being impacted by this blood clotting issue, hence also prescribing Clexane to thin the blood, ensure sufficient blood flow to the endometrium and embryo etc.

Oh I hope hope hope this makes all the difference in the world. Just to be Dr BDT, I would be pushing your FS to prescribe you Clexane, to me it was the magic injection that I totally attribute to finally getting a positive.

I hope this helps some, will be praying with all my might xx