Calamine lotion didn't do anything for me. The Dr's in the hospital gave me antihistamine which did help for a little while. Also I forgot to mention that OC inhibits your bodies ability to take on Vitamin K which helps in clotting. You should get some Vitamin K supplements or you and your bub could have bleeding issues during birth. My OB also told me that I can never go on the pill now. Apparently people with OC's livers can't cope with to much estragon and it can cause you to have a stroke.