MTHFR testing questions

[LionsandBears]

To anyone who has been tested for MTHFR, were you tested for both C677T and A1298C genes? I see the test for C677T is Medicare rebateable, but can't see if A1298C is. My GP doesn't know if it is.

Did you get tested for anything else with it?

Who organised the test and how long did the results take? I can't get in to see my GP for a while.

If you were found to have MTHFR, we're you prescribed 5-MTHF instead of folic acid? If so, how much and where did you source it? Is it available OTC in Australia or do you need a prescription? I can see it's available online from the states. Are you taking anything else, like B6, B12, baby aspirin or whatever?

How long did you take any of this before TTCing again? I've been told different things. One person says 1 month, another says 3 months.

Did a MTHFR affect life insurance if you have it?

TIA

[LionsandBears]

Bump

Also - was your partner tested? Apparently both parents being affected increases the chance of something going wrong.

[LionsandBears]

Anyone?

[Beatrix]

I have this gene.. I had a blood test to determine it, that was all.

My ex husband or current husband have never been tested, but mine runs in the family.

When i was pg i took 5 times the amount of folate rather then the normal recommended dose.

[Astrolady]

Bump

Also - was your partner tested? Apparently both parents being affected increases the chance of something going wrong.

Yes Andrew was tested a few days after I was. I have it. He doesn't.

Here was my post when I was diagnosed - https://www.bellybelly.com.au/forums...thfr-gene-253/

[LionsandBears]

Thanks Ness & Kathryn

Kathryn - did you get a prescription for the extra folate? And was it folate or folic acid? That's if you can remember.

There's a big difference, apparently and folic acid, which is synthetic, can actually block the receptors for folate, so apparently if I have MTHFR, I shouldnt be taking folic acid. I need to take activated folate.

[meow]

I'm looking into getting our family tested (mostly my autistic son) so thanks for your thread because you have a lot of questions I was unaware of. All I know if that synthetic folic acid isn't meant to be much use if you have MTHFR. I'm considering just supplementing 5-MTHF anyway and seeing how we fare on it.

[LionsandBears]

I was actually thinking of asking you, as the link to autism is pretty clear. If you want more information, look up mthfr dot net. It's run by a naturopath in the States whose whole family has various versions of MTHFR.

Apparently, it is possible to both under methylate and over methylate folate. So the 5-MTHFR may not be good if you over methylate. I'm thinking of trying it anyway, whilst I wait on getting the blood tests & results. I do know I've always had high Folic acid levels when tested, which may mean I undermethylate. There are other indicators, including the ADD and other health issues. Interestingly, for the A1298C mutation, it's recommended to heal the gut first. I see a link to GAPS. Obviously, I am most interested in any possible link between folate methylation and DNA mutation (there has been shown to be a link between MTHFR and T21).

I also need to find out the difference, if any, between 5-MTHFR and L-MTHFR as a supplement. They may be the same thing. You need extra B6 & B12 with it as well, as the high folic acid/folate can disguise a B12 deficiency. Anyway, I'm going to order some stuff off iherb, or of the mthfr guy's website.

Meanwhile, I've started green smoothies as a way to increase my daily dose of natural folate.

[Astrolady]

To anyone who has been tested for MTHFR, were you tested for both C677T and A1298C genes? I see the test for C677T is Medicare rebateable, but can't see if A1298C is. My GP doesn't know if it is.

I was tested for 2 variations, but can't exactly remember what two they were


Did you get tested for anything else with it

Sorry can't remember . I don't think so though. It was 8.5yrs ago

Who organised the test and how long did the results take? I can't get in to see my GP for a while.

It was done through the obstetrician I was seeing at the time, and picked up late in my pregnancy with Lachlan

If you were found to have MTHFR, we're you prescribed 5-MTHF instead of folic acid? If so, how much and where did you source it? Is it available OTC in Australia or do you need a prescription? I can see it's available online from the states. Are you taking anything else, like B6, B12, baby aspirin or whatever?

I had to take folate and vitamins B12 and B6. With my next pregnancy I was put on baby aspirin.

How long did you take any of this before TTCing again? I've been told different things. One person says 1 month, another says 3 months.

Did a MTHFR affect life insurance if you have it?

I don't have life insurance

TIA