I have just had my 2nd miscarriage in 12mths. The first time, I started bleeding at 9wks and the baby's HB stopped at 12wks. I had 3 d & c's because after each one i still had 'retained product'. Finally 6wks after the 3rd one, the last of it passed on it's own (3mths of bleeding all up).

This time, i started bleeding at 6wks and the baby's HB stopped just after 7wks. I didn't want any more procedures so soon so decided to try medication management at home, with my OB's approval. I used misoprostal with some effect but still had 'retained product'. Tried two more lots of doses of misoprostal. Still have a little bit left and 2wks after i started the treatment my HCG is still 140. My Dr thinks it should be close to '0' by now so he has recommended I consider methotrexate. I'm scared of taking it because I'm worried about side effects. Like how long would I have to wait before i can TTC again? Are there risks of birth defects if I don't. My OB seemed to think i could try again in one cycle (but he seemed a bit unsure and is sending me to an oncologist for an opinion and to do the treatment, he's not doing it himself).

I think i'll also ask for one more blood HCG test in a week so they can see if my levels have dropped a bit and if so maybe continue the 'wait and see' approach.

Has anyone else had this dilemma or had methotrexate treatment for pg loss? Any advice?