Any advice for someone with multiple miscarriages due to trisomies

[buliej]

Hi

I have had 3 m/c's in 11 months due to trisomies (chromosonal abnormalities). Both DH & I have been tested and the conclusion is that these are spontaneous trisomies (they have all been different chromosomes) due to age - meaning that we are not genetic carries of any chromosonal abnormality.

I get too few eggs for them to try growing to blast and doing PGD - my FS thinks the costs associated with this (both $ and risk of loss of a good embryo) outweigh the benefits for my situation.

Has anyone been in a similar situation? Do you have any suggestions? I don't know how many times I can go through the process of getting a BFP - only to m/c after 5/6 weeks.

Thanks

[DaintreeDream]

I do not have any advise and I am so sorry that you have miscarried as a result of trisomies, my DD1 has a chromosome abnormalilty and my DD2 has a problem with her heart which they thought was linked to a trisomy, both of these mean a stay in NICU at birth and surgery as an newborn.
Both are random, not linked our genetics passing them on, I am 27 and DH 31 so we shouldn't be high risk, and no other cases in the family.
I know the feeling of not knowing if you will ever concieve a healthy baby and the constant worry even though I have been fortunate to carry to term (at least with DD1 so far).
I am sorry I do not have anything to offer I just hope that you are able to concieve your healthy baby soon.

[diannescruffy]

Hun, I am so sorry for your losses. I really hope and pray that one day you will be able to carry a child full term and get to hold them in your arms. Have you been told which Trisomy your babies had? Three years ago I had a baby with Trisomy 13 who was stillborn at 24wks but then went on to have a beautiful healthy little girl. I will keep you in my prayers and if you ever want to chat please feel free to PM me.

Regards,
Dianne
Emmanuel born sleeping 24wks
Trisomy 13

[buliej]

Thank you for your responses. I guess my fear is that because of my age, I have no hope of having an egg without a chomosomal abnormality. I'm not sure if statistically, 3 out of 3 indicates this or whether 3 out of 3 abnormal embryos is not that unusual at my age and that others have gone on to have a baby. I wish I could compare myself to someone younger who has had success but I really think that age is the defining factor of my situation.

[diannescruffy]

Hun there really is hope of your carrying a healthy child, many women have had healthy children in their 40's. I was 36 when I had Emmanuel who had Trisomy 13 then at 37 had a healthy child. Wishing you all the best.

Regards,
Dianne
Emmanuel born sleeping 24wks
Trisomy 13

[DaintreeDream]

I completely get where you are coming from and I hope that someone comes in that has a similar experience to you.

I understand what you mean in regards to the statistics and wanting to find out if the 3 out of 3 is a direct result of your age, I suppose I am in a different kind of boat where my babies have the abnormalities yet I am mean to have age on my side.

I really do wish you all the best in you TTC journey.

[buliej]

I think I'm coming from a pretty raw place as my latest loss was just confirmed yesterday - although I was certain of it for about a week.

I hope I didn't come off as dismissive of your respective journeys - although our struggles may be unique, I think the feelings, frustrations, joy, sadness and true appreciation for the miracle that babies are, are understood by everyone who posts in these threads. It helps so much to know that I am not alone - although I wish none of us needed to find this part of the forum to begin with - can you imagine a world where no one has anything to post in a Loss thread because there are no Losses - how wonderful that would be.

[DaintreeDream]

I could never even begin to imagine where you are coming from so please do not feel that you came across in that way.

May I just add that I have also had 3 losses, 2 at 12 weeks and 1 at 5 weeks, the reason is unknown as I did not investigate.

I am so sorry if I have made you feel any worse it was not my intention .