I personally know of a couple 3 IVF cycle's, they had a DS, then had one naturally, she was 39

I concieved 2 naturally bofore ART, unfortunatly lost both, and am on my 4th IVF cycle with no luck, all within 3 years

There is a very interesting thread, that gave me hope, and took away that whole "is my mind affecting my pregnancy chances, thought pattern", here on BB