I believe it works, but DD used to fall asleep on the plane as it was taxing to the runway. And she'd sleep the whole flight. Do the first doses while you are waiting to board, while he's awake, so he's calm before you get on the flight, and just top him up every 2/4 hours (whatever it says). Now just because its herbal, doesn't mean its not dangerous. You must follow the directions. If he misses one of the first four doses, you can't make it up. Just go onto the next scheduled dose, even if its a few hours away. And don't use two Brauers products at the same time, as you'd be double dosing on ingredients. Best to talk to your pharmacist of nurse.

Make sure he has his comfort toy/blanket etc and dummy, as he'd need these more.