I have HUGE problems getting Hudson to take most medicines too. It usually takes two of us to hold him down and get it into his mouth, and then often it is spat back out at us. Panadol is one he will not take, however I bought some neurofen just recently when he was teething and have found he will actually take it, and even open his mouth willingly if I didn't get it all out of the syringe the first time. Obviously to him it just tastes nice so he is happy to have it, but this is the only medicine he will happily take. You may have already tried it, so if so just ignore, but just a suggestion in case you haven't, as neurofen is also meant to treat pain and fever. HTH.