I have used Infants Friend since Nic was about 3 weeks old. He had terrible colic and reflux. I found infants friend to work really well, but I have found the Pharmacy mix (asmentioned in Caro's post - the Colic Mixture) to be sooo much better. Straight after a feed, I give it to him and he brings up the wind almost straight away. It is really gentle too and he doesn't spew as much because his wind comes up so gently.