Oh yeah....my mum wears a lot of perfume and Grace used to scream scream everytime she picked her up. We worked out what it was when we noticed the pattern of perfume on people..got my mum to stop wearing perfume when around Grace and amazingly she didn't cry anymore. So I would say that there is a good chance that is the problem. It makes sense though...people tend to spray perfume on or around their neck and then that is where babies faces get put when they are held..they probably can't breath! Hope it all settles down with no perfume!