Oh Ash I'm so sorry you are going through this at the moment, especially since you are home alone. I'm racking my brain trying to think of something for you to try. Have you tried a bath? Nappy free time? Olivia went through a day like this and I just had to wrap her, put her in her cot and let her chuck a fit for a little bit. It nearly broke my heart but she did settle. What about putting him in the car and going for a drive around the block to try and settle him? Does he like his pram? How about putting in that and walking around the house?
Have you tried putting his panadol in some water in a bottle to try and get him to take it that way for you?'
Sorry that's not much help but I'm sending you heaps of hugs. Hang in there Ash you are doing a great job.