Nothing too drastic for me, but I was definitely more emotional around day 3-ish. With DD1, I remember crying because all her undershirts were too big... With DD3, DH wanted to send the older two to his mother's house so I could rest, and I bawled when they left! I wanted all my babies at home!
But thankfully, my emotional/hormonal state didn't last too long. Before long we were back to "normal" again.