The active component of marijuana, delta-9-tetrahydrocannabinol (THC) is fat soluble and is rapidly distributed into brain and adipose (fatty) tissue. The analysis of breastmilk in chronic heavy marijuana users shows an eightfold accumulation in breastmilk compared to plasma. Infants exposed to marijuana through breastmilk will test positive in urine screens for two to three weeks.
Breastfeeding infants absorb and metabolise THC and their exposure occurs at a time when growth and development, particularly glial and myelin formation in the central nervous system, is progressing at a rapid rate (Tennes et al 1985; Astley & Little 1990). Animal studies have shown that structural changes occur in the brain cells of newborn animals exposed to marijuana through their mother's milk. Marijuana purportedly impairs DNA and RNA formation. Although long-term studies have not been completed, results observed in humans suggest serious and long lasting effects (Astley & Little 1990).
The use of marijuana by breastfeeding mothers is contraindicated by the American Academy of Pediatrics. The long-term effects of early exposure, especially on the infant's rapidly-developing brain are unknown. Breastfeeding mothers should be advised not to smoke. It has been suggested that breastfeeding should be avoided if the mother is a heavy user and
withheld for several hours after occasional use. Measures should be taken to reduce the infant's exposure to sidestream smoke as discussed previously.
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