You can give panadol and nurofen at the same time. I've had to do that for a couple of nasties we've had when temps soared to 39.5. It's what the hospital gave DD2 when she had pneumonia and was in for a few days.

If you call health direct the nurse will ask a bunch if questions an let you know if you can wait til morning or take them to a hospital. Once they even called an abundance for me the situation was that bad

Hope you've had some improvement