We have at times (when the medicine has been yucky tasting) force the kids to take it. DH will hold them down so they cann't move, I will force the syring in their mouth. Now the have to be laying on their back for this, and you have to dribble it out of the syringe slowly so there isn't enough at anyone time to spit it out from that position - you also need to make sure that the syringe stays between their teeth the whole time (if they can close their teeth or their mouth, they will still be able to spit it out, even the small quantities). It can be a slow torturous process, but sometimes you just don't have any other choice. Also be prepared for some spluttering, but provided you only put very small squirts in at a time, they shouldn't choke.