i do have alot of experience with predmix but i really dont think you will want to hear about it
My 4yr old Ds has Athma and he has been bad enough to need Predmix 5 times this winter and he turns into a horrible aggressive non sleeping child from about day 2 of taking it till about 3 days after he stops it is horrible but it helps him breath and he needs it. He is on a higher dose of 5Mls tho so not sure if that would change it. I really trust his Dr though and if he prescribes it Ds really does need it so that is why we continue to use it.

I hope your DD improves quickly. I found i did sleep a little better when DS was taking it cause when he did sleep he wasnt wheezing and coughing and spluttering so i was able to relax enough to sleep

Hugs!!