Hi there littlebear,

What you are describing could be a few different things. Lots of babies have a growth spurt at 8 weeks, and become unsettled at that time, so it could be that. It could be reflux - Losec can sometimes not be effective, or he could have had a particularly bad reflux that caused him pain despite the Losec. Losec doesn't cure reflux; it inhibits acid production in the stomach, so the reflux still occurs, but because the stomach acid is not as acidic, it is less painful and damaging.

I think a check-up with the doctor is a great idea.