2 of my bub's have had reflux. DD2 was my first screamer. Life was impossible for the first 10 weeks.
DD3 started at about 2 weeks. At 5 weeks she started sleeping through the night, but was impossible through the day. She only slept through coz she was so exhausted from being awake all day.
Once I realised what it was though, I could deal with it & make sure she was comfortable. I have taken her little co sleeping bed out of her cot, so she's flat, but will put it back in tonight because she hasn't slept properly since it came out.
Everything has to be elevated. She almost always pukes on the change table, coz she's down flat. The sling was my saviour.
We haven't needed any meds & she's improved alot quicker than DD2 did