I'm no expert but I remember once reading an article by a doctor who'd been working in Africa/Middle East. She mentioned talking to women there about menstruation who didn't know what it was. Due to the age they were married, many of them had gone through years of pregnancies and breast feeding without ever having one AF (Really sad to think how young they must have started )
I've read in a Francesca Naish book that optimum spacing is about 2 years between conceptions. That has to do with ensuring your body has built up all the nutrients for the next bub without depleting mum too much. Like all theories, everyone should evaluate their own situation. We sure won't be waiting that long (hopefully).
If you're really unsure, you could get blood tests on hormone levels, but if you just give things a go and see what happens, there may be no problems at all. I do understand the fear of having something wrong when you've already lost one baby to a disorder(our son died from a genetic problem). My understanding is TS is a one-off, so it shouldn't happen again.
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