As Rach said, Isabelle's condition sounds very much like anencephaly which is a neural tube defect, as is spina bifida.
DW is taking 5mg folate daily due to my family history of spina bifida.
Where there is a history of NTD doctors will usually advise you to take 5mg, or possibly a different dose depending on your circumstances.
Remember, NTDs occur within the first few weeks after conception so it is important to start taking folate as soon as possible so that your body has sufficient levels before you fall pregnant. Taking it after about the third week of pregnancy has no practical effect on the likelihood of a NTD as the basis for the area concerned is already formed.




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