Thanks to everyone for their comments. I don't even understand the diagnosis at this stage - I read a lot - and I don't have any symptoms of PCOS - ie regular cycles, no excess hair/pimples.. Ultrasounds on two occasions have found "no evidence of pcos", on day 21 my progesterone was 6 the month I fell pregnant. I went on clomid late 2003 for 4 cycles and have been on metformin for about 8 months. I had just started the metformin when I fell pregnant, but nothing since. My specialist has decided I don't ovulate and I haven't been given a progesterone test since September 03 so I guess they are predicting no changes, but nothing physical for me to see it's this way. I get frustrated because I keep being told to come back in a couple of months and nothing else happens. I've lost some weight and continuing to lose more but still nothing.... I've also heard that long term use of clomid is harmful? Is this true? I'd like to give it another try. Hubby's sperm is fine so it's all just me - and that's so hard to know it's all because of me. I know the progesterone is supposed to keep climbing after ovulation, so is this why I miscarried? because it didn't sustain the levels it was supposed to? Ahhh normal human beings in ordinary lives are telling me more than the docs!! #-o PS What is RE?