My DH works from 2:30pm til 12:30 at night, is usually in bed around 2am-ish and get's up between 10:30 and 11:30. We are in a one-story house that isn't all that big either.
I used to worry about keeping the kids quiet, and he used to be really sensitive to the slightest noise, so we'd go out in the mornings to get things done that needed to be done.
After a while he just started sleeping through anything and everything so I don't really worry about it too much anymore, having said that, he's been doing it for almost 6 years.

Sorry that's probably not much help, if he's going to be doing the shiftwork often it might be work building a granny flat.