I am currently using prog pessaries and am nearly 30 weeks although I have only been using them since conception. With DD I also used them from conception to 36 weeks as my body just doesn't make it's own prog in preg (not enough anyway) so without the pessaries I just couldn't have a bub! Anyway, they are nor really a problem at all. The only thing to keep in mind is that they can cause itching in some women which can be solved with inserting a Vit E tablet at the same time and alsom as the prog is encased in a waxy coating, that waxy coating has to go somewhere so you need to use some pantyliners. Otherwise for me, it is a tiny price to pay for a bub!