Jacob would go off his food when teething as well, and he'd point blank refuse any form of teeth cleaning! It was a real battle. Have you tried some bonjela to see if that works, or perhaps the 'Brauer's range which has a teething formula? Just an idea anyway (you can get these at chemists).
Jacob hasn't been a good sleeper either, Heidi, so I totally appreciate how hard it is on you all! When you say he wakes after 45 minutes, it sounds like he is stirring after a sleep cycle and is having trouble resettling himself. I found that Jacob's sleep would come and go, in that some weeks were good and other weeks absolutely positively rotten! Teething certainly didn't help, that's for certain!
Have you tried using some music, some gentle patting/rocking with him at all? Jacob responded well to the patting/rocking when he was James' age, as well as a sleep ritual which was the same every single time he went to bed - being consistent and persistent are the keys I think!
I don't have a miracle cure unfortunately - if I did then Jacob would sleep well now LOL but he still has a lot of trouble with it!
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