I've been on the pill since August mainly because I finished Zoladex treatment and was still waiting on endo operation so they didn't want me getting AF but I am still on it now (thankfully only until tomorrow) for down reg IVF cycle. I have had bleeding as well not related to AF as I haven't taken any of the sugar pills & I remember years ago when I was on the pill I used to get bleeding between periods as well. Weight gain - I've gained about 3 kilos since being on it that I can't lose no matter how much I try. I think if I wasn't trying to lose it though I would probably have gained more. Headaches I'm getting alot of lately but I think that's due to the Synarel....