Wishes, my second stim cycle was a regular down-reg cycle with lucrin, but I was given orgalutran on top of it as my E2 levels were getting way too high. It's not a "normal" thing to happen, but it's not unheard of. I was on it for a different reason to you, but I can certainly say that it has been done before.

I can't believe the price they are quoting for lucrin! I'd pay about $150 for it through my clinic, and it wasn't that long ago. Perhaps you could ring around a few pharmacies to see if you can get a better price? From memory the orgalutran and cetrotide are also pretty expensive, so it might just be worth costing things out in full to see which would be the better way.

In many ways, every single cycle you do is a bit of an experiment. Each time they learn a little more, and each time they do things a little bit differently. For me - we first had to learn that I don't respond to synarel. Then we had to learn that I don't respond to low doses of puregon... then that I respond too well to high doses of puregon... then it was a case of figuring out that it's still a problem if we start high and drop down quickly... finally we figured out that I need to start at a slightly higher dose of puregon and be monitored very closely as well as follow a very strict diet and take anti-fungal drugs in order to finally achieve success. Most people don't need to go through even half of that!

All you can do is hope that they have learned enough to get to EPU this time and that things will work from there. They may then learn that you need to grow your eggs a little longer than normal (or for a little less time than normal), but they tend to just go with averages and what works best for most, start there and vary where necessary. There's no way to know exactly what will happen until you get in there and try it.

I hope all of that makes sense and isn't too depressing.

BW