thread: Just starting ICSI

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  1. #1
    Registered User

    Apr 2010
    Gold Coast
    100

    Hi from a fellow Newby!

    Hi Babydownunder,

    A fellow newby here (in fact, this is my 1st post, although I've been lurking for a few weeks). I'm just starting my first ICSI cycle, after never using any fertility treatment before, so I'm in a similar boat to you. Anyway, I just did my first ever Puregon shot this morning. I'm happy to report that it wasn't bad at all. I'm not great with needles and I couldn't even feel the shot as it was sitting in my belly. Now it's been an hour, and I feel a slight twingeing at the injection site (not painful at all), and that's about it. So hopefully that will take away a little of the trepidation for you. I start Orgalutran the day after tomorrow (slightly bigger needle), so I'll re-post and let you know if I found the Orgalutran just as easy.

    My biggest fear is that I just found out 2 days ago that I have low AMH (6.9), so now I'm concerned about whether I'll even respond to the shots at all. Before I got the results, my doctor had told me to start off with 225 units of Puregon, but, in light of the results, he bumped me up to 275. (I should mention that I turned 38 2 months ago and have never been pregnant. Before getting this result I had thought that the reason we hadn't been getting pregnant was DH's poor morphology (1-3%).) I was pretty relaxed until I got my AMH result back, but now I'm feeling pretty stressed. I won't get to talk to the doctor about it until I go in for my scan next Wednesday. Oh well . . .

    Now I'm also wondering if I might have mistakenly given myself a larger dose of the shot than I was supposed to, but that's for another thread.

    Good luck to you and to everyone else who's cycling this month!

    KitKat72

  2. #2
    Registered User

    Apr 2010
    1

    Smile Just starting too!

    Hi Babydownunder,

    I have just begun my first IVF cycle too. I started my injections on Thursday. I don't know about everyone else but I am over analysing my body to try and pick up any changes from the drugs! So far I have had a bit of abdominal cramping and feeling of nausea right after the injection and in the morning.

    My biggest fear is the egg collection - I think I have read too much about how it can be painful. Some other members may be able to shed some light on this or give some advise!

    As we live in the country trying to juggle work schedules and egg collection schedules makes life a bit more difficult but we are looking forward to our first try.

    This is my first time using a forum. It would be great to hear how others are going and how they are feeling.

    Good luck

  3. #3
    Registered User

    Apr 2010
    4

    hi babydownunder,
    it is all very overwhelming and extremly strange when u do your first cycle! i have done 1 cancelled cycle and 1 stimulated (icsi) cycle. unfortunatly my embryo transfer was unsuccessful and we had 0 frozen embryos so im about to start another stimulated cycle.
    i was VERY concerned about egg pick up as well but i have to say i was pleasntly surprised with the whole procedure.
    i know everyone is different though.
    i considered a GA but my doctor uses sedation and has an anesthetist there who can "knock u out" if need be! i found i was sleepy during part of the pick up . my husband tells me i was awake for most and chatting however i dont have a memory of the event ( thanks to midazolam a drug they use). i was a little sore after the fact but it has definatly taken the fear factor out of it for me an im much more relaxed going into this next cycle.
    i hope this helps u

  4. #4
    Registered User

    Oct 2007
    Caroline Springs
    2,341

    Like many of you, my biggest concern was EPU. My clinic routinely uses GA during EPU, and I've always been nervous of GA's (irrational fear of never waking up...). I asked about having EPU without a GA, but was told that they do all their EPU with it, so I went along with it. This cycle (I'm on day 4) I'm going to ask again if there is any chance at all of not having a GA for EPU. I wasn't happy with the outcome last time. It was a bit of an unusual situation though. I was in quite a bit of pain a couple of days after the procedure (more than I thought I should be) so called my nurse who assured me that it was normal, so I just dealt with the pain for the next week or so until it went away. Two and a half weeks after the procedure I discovered that I had stitches inside my vagina that I had not been made aware of. I freaked out! It was after hours on a friday night and I couldn't contact anyone until the next day. Even when I finally spoke to a nurse the next day, she had no idea why I might have stitches and had to ask a more senior nurse. It turns out that occasionally if there is some excess bleeding they will put in a stitch. They were disgusted that I was not told after the EPU, and even more amazed that I wasn't even given any after-care instructions. Turns out it was just a really bad situation that almost never happens. BUT, it makes me even more scared about going under a GA this time around. I'm also still skeptical about what happened because there was not just one, but three stitches! It's now been about 6-7 weeks and there is still one that hasn't dislodged and come out...

    Hmm, gosh, I'm really not making you feel better about things am I? In regards to the pain of the EPU, I think I had a bit extra from the stitches, but even with all that considered, it wasn't excruciating pain. I'm not able to take pain killers and I was still able to move around ok, and even carry my baby who was 9-10 months old at the time. Just take it easy for a couple of days afterwards and you'll be fine The needles aren't exactly fun, but it's the mental part of things that's the worst. The actual needle really doesn't hurt (a mosquito bite ) but it's the mental aspect that makes it hard to stick that silly little needle into your own skin. When I did my first needle I sat there going "ok, one... two... three..." and then not moving the needle any closer to my skin, LOL! Took me about 5 countdowns to finally do it. I've heard some people say it's easier to push it in really fast, but I still do it moderately slowly because it seems less 'stabby', hehe.

    Good luck with everything! I hope you can tell us some wonderful news soon!

  5. #5
    Registered User

    Mar 2007
    Sydney
    1,365

    Firstly I just want to wish you all the best luck on your cycles!!
    It can be a very scary time BUT I promise the outcome is very well worth it

    The EPU was my bigest fear as well so you are not alone My first cycle I had light sedation and really can't remember much of it. My second cycle had nothing and was wide awake for the procedure.
    There is some discomfort after the EPU, but nothing like what I expected and really just took it easy for the following couple of days. Nothing like a cozzy bed, panadol and a few trashy mags...LOL!!

    Best of luck ladies

  6. #6
    Registered User

    Oct 2007
    Caroline Springs
    2,341

    Nicole, I've been meaning to ask you about your second EPU since I first sound out that you didn't have sedation or anything... Just wondering what they gave you so that you couldn't feel the procedure? I'm guessing you have something so you couldn't feel the needle? I'd like to know what to discuss with my FS to see if I can do the EPU without a GA.

  7. #7
    Registered User

    Dec 2009
    Melbourne
    57

    2nd down reg ICSI cycle

    Hi all,


    Mylitta - I'd imagine EPU under light sedation would require local anaesthetic. Fancy them forgetting to tell you about the stitches. I really don't know what to say about that. I'm a nurse, and that is major. Major, major, major. I'm not quite sure what you mean about the last stitch hasn't dislodged yet. Do you mean disolved? Sorry, not up with all the gynae. Yes, and as for the needles, I watch patients give themselves insulin injections, and I find that most of them do it nice and slowely, so I did it that way and it was pretty OK.

    Nicole - that sounds great that you didn't need anything. I wonder why they encouraged me to have a GA on my first cycle. It wasn't even really suggested that light sedation was an option. I will ask tomorrow about that option.

    Dreaming - I'm in the same boat as you. The cycle in November only produced one embryo. So this time they will have me on Gonal-F 225 units injections instead of 150 units and hope for more follicles this time. Only had 5 last time.

    Southaus74 - , I hope everything is working out right as you would be close to egg pick up now. Hope the trips into town aren't too much trouble, it would add extra cost as well.

    Kitkat72 - as well. this is probably my 3rd or 4th post. The forums have been very informative. Could you tell me what low AMH is? I hope the cycle is turning out for you.

    Babydownunder - I hope your first cycle goes well.

    As for me - I've had one cycle in November and now on a second cycle, going for first scan tomorrow to check whether uterus lining is ready for Gonal F injections. On my first cycle my concern came 2 to 3 days after embryo transfer when I thought I had a UTI. I ended up going to the emergency department at 1am, just in case I needed antibiotics, after all that effort, I didn't want a failed transfer because of a UTI. It turns out that it was just my body still healing from EPU and the pain happened when I voided and the bladder deflated. It got me really worried. I realise they must do a bit of poking around to aspirate each follicle. Anyway, within a few days it wasn't an issue.

  8. #8
    Registered User

    Mar 2007
    Sydney
    1,365

    Mylitta, I think they only used some type of local in the area where they draw up the eggies.
    I think that was the worst of the pain I felt, the rest was like really bad period pain.
    I'll be honest it did hurt and I just talked to DH and just watched the clock but being awake for the 20min it took for the procedure I can live with that as when I had the light sedation when I woke up the nausea feeling was something I didn't want to re visit....oh yeah and going home and sleeping for 8 hours too!!
    It was also really exciting counting eggs with the nurses
    Oh yeah they did put a cannula in just in case and there was a anaesthesiologist there and I had to pay for him but never needed it.
    Some FS will not do the EPU unless you have at least sedation, but all you can do is ask.

    timeforafamily, how scary for you going to hospital!! I guess don't take any chances hey.
    Best of luck on your second cycle....fingers crossed for a second time lucky