Pessaries vs Crinone

[MummaSue]

I used crinone and it was gross. But I hear the pessaries are too!

The preference lies with your FS xxx

[dusty]

I think crinone is more effective compared to pessaries especially if the pessaries are used vaginally. At my clinic they now do pessaries rectally and have had better results with maintaining progesterone levels.

I have normally used crinone in the 2WW and then pessaries when pg. Actually last cycle I used both until 13 weeks pg to ensure my P4 levels stayed up but I think that was unusual (2 crinone and 8 pessaries a day!).

Crinone is absorbed more fully into the uterus and may not show up as high on the blood tests which can cause some people to worry but it is quite strong. Both have side effects but I think the crinone is more iterating on the cervix and can cause some brown discharge.

I can recommend the pessaries rectally as you are sure they have stayed in longer (ie don't leak like they do vaginally) and absorbed more. That said after using them until 13 weeks pg they irritated my bowel too.

Well that is probably TMI but I took a ridiculous amount when pg with my DD so got to know them both well.

[oneday86]

I used pessaries with all my cycles during my first STIM cycle and i didn't like them, my body didn't really absorb them and by my last FET i was on 4 a day! and still had a low progesterone level. You also have to lay down for half an hr after inserting them morning and night and it does come out. For this STIM im on crinone, i havn't started using it yet but im hoping i will get better progesterone levels this time, but don't let this worry you as it could just be my body that dosn't absorb it very well?
Goodluck xx

[kass]

I've used both - crinone for fresh transfers, pessaries for frozen - I've never asked why they do it that way - maybe since the crinone has an applicator it's better if you're 'sensitive' after a collection! - pessaries are a lot cheaper, both can be messy. I think they're meant to be equally effective, but like everything else different people respond differently - my last level was 105 from one daily at the end of tww (pessary)

[Aimee]

Hi

Thanks so much for the information!!!!!

My FS has said I can use either.....I have heaps of left over crinone from a cancelled cycle so I guess I can switch if the pessaries aren't working properly.

When did you start your progesterone support, was it after EPU or after transfer?

[Amy_jellybean]

Hi Aimee,

I used Crinone as well and had the same problem with it not coming back out - not a fan!!!

[MummaSue]

Hey hun, I started using the crinone 3 days before embryo transfer.

Good luck babe xxxx