I have done 21 IVF four of which were PGD. Of the PGD cycles there was only ever one "normal" embryo for transfer. PGD is tuff going because the stats on actually getting to ET are less than the alternatives. But at least with PGD you know are forgoing the TWW - IYKWIM.
We ended up doing the PGD because of suspected dodgey older eggs and the high number of failures - plus I've had two early losses.
On a good note, my DD is our IVF miracle and my DS is our natural miracle. Obviously having had such bad results with PGD my DS pregnancy was filled with angst and we were preparing to do an amnio.
All is great now.....so you are so right....where there's hope there is a definitely a way..
Best of luck on your IVF journey - may the rollercoaster ride be kind to you....
Meredith - I will keep you posted on this IVF cycle with PGD. Feel free to send me any questions you may have.
Magic - thanks for your post. 21 cycles is intense - is that including FET? When you did PGD did you get one normal embryo per cycle, or was that out of four (resulting in DD)? How does PGD forgo the 2ww Sorry, I'm a little confused But so happy you are now finally exhaling!!
AFM - IVF nurse rang following BT this morning to let me know to expect AF around Sunday (Day 32 - normally 28/29 day cycle). She believes the Provera has not delayed my AF. MC Investigation Program. DH's SCSA came out at 12, which our OB was very happy with. The only thing that came up in the tests is I have a double-gene mutation for MTHFR, which means I am at double the normal population risk for MC. Iam already taking Megafol which is about the only thing they can do about it. Might explain our March loss (which was chromosonally normal). We bipassed the NK cell biopsy, which I am now regretting a little. Our extended karotyping was normal, so this means IVF with PGD really is the best way to go as the other two losses were probably due to my declining egg quality.
WTH - glad your DH SCASA result was good but sorry about the gene mutation for you. Hopefully any embie that can survive through PGD will be tough enought to stick it out anyway!
Wanted to make general comment re SCASA but DS is awake and cranky so BBL!
WTH, I recall that there is more that can be done with MTHFR apart from the massive doses of folate. I only have a single gene, so I'm apparently ok there. I think it was also B vitamins and aspirin - at work at the moment so I can't dig out the information I came up with as it's at home. Do you know if your homocysteine levels were normal? That's supposed to be an indication of how bad the MTHFR problem actually is.
HI BW - my homo levels were excellent. I have been taking Megafol since the first loss so my folate levels, which have been checked, are fine. Amongst the ****tail of vitamins I take, I also take B12 as I am a vegetarian. I would love to learn more from you about anything else I should do as my OB only mentioned megafol.
Finally managed to get back on.
Just interested in all the talk on here re SCSA test. i asked my FS about getting DH to do it and she said that the MOnash IVF andrologists don't believe it has much validity so don't reccomend it at all. Apparently there is some new and better test coming up soon. She did also make the logical point that even if test came up not so good then the only treatment is antioxidants... so just take them anyway. I put DH on menevit a few weeks ago so will push him to keep on it but bottom line is not doing the SCSA test.
Wondering what other's FS's have said about the test and the point in doing it?
WTH - Sorry about the gene mutation, good that you know that PGD is the right way to go really hope it will solve this for you. The SCSA result for DH sounds great.
Why do you regret bypassing the cell biopsy and is there not the possibility to do it now?
Thanks for the tip with the pineapple juice, will definitely try this.
Tam - thanks for the info about diet, my DP is not very good with his diet but at least he usually eat anything you put in front of him. So took your advice and made fruit smoothies yesterday - and will make some fruit salad today
Also good to know that 4 weeks of Menevit made such a difference if my DH result is not any better will get him some Menevit, at the moment he takes Blackmores men's performance multi.
Meredith - actually very relieved to hear that your FS thinks the test is not so important as the result for my DH was quite bad, he has taken antioxidants and done another test of which we'll get the result next Wednesday. MY FS said that she'll use PICSI instead of ICSi if the result is bad which sounds to me as if there is something that can be done but will ask her about it in detail when I talk to her.
Magic - Great to hear that you were successful after so many IVF cycles - was it a PGD cycle when you got pregnant?
AFM rang the clinic yesterday to talk about starting the Lucrin, since I am already pill popping it seems I can start anytime, have now tentatively made Oct 29 as the start date. Also made appointment for Acupuncture at the Rozelle clinic. Had a big meltdown afterwards. Wanted to do this for the past five years and now it actually starts finally realising how nervous I am about it, hopefully the acupuncture may help with this.
But so happy you are now finally exhaling!!
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