You don't need to wean onto prednisone. Things like metformin you do, because it takes a while for your digestive system to be able to tolerate it. Prednisone doesn't have drastic side effects like that, but it does effectively switch off the body's natural production of cortisol (? I hope I'm remembering the right name here!). Stopping it suddenly can send your body into an adrenal crisis as it no longer makes an essential hormone. Weaning off slowly allows the body to slowly resume the production of natural steroids so everything is ok.
As for me... for the arthritis... I need it now. Once I'm pregnant, the hormones my body produces take over and the arthritis all but disappears. By the time I got to 7 weeks I was feeling as though I could stop the prednisone, but I spotted when I did. So for me it's just a matter of staying on it a bit longer than arthritis pain indicates is necessary and then weaning off once the pregnancy is established and secure.
You've just got to remember that there's a number of different health conditions interacting here, and what's necessary for me isn't always necessary for other people with less complex medical situations.
PP, I'd suggest you email Dr S and ask. I think that he'd want you to start at 10mg at the beginning of the cycle, and then increase to 20mg and EPU/transfer (although we did ovulation for my natural FETs). But... I really couldn't say for sure that is what he'd do. For me, it was a situation of adjusting the prescription that another specialist had given me rather than starting a new drug.
As far as I know, it should have no effect on ovulation, but different drugs effect different people in different ways. Small example - I have to take my prednisone in the mornings. My rheumy prefers his patients to take it at night so that there's some drug in your system to overcome the morning arthritis horrors. If I take it at night I simply don't sleep at all. Very unusual side effect, apparently, but even when we tried a split dose - one 5mg tablet at night and the rest of my dose in the mornings, I still didn't sleep.
Anyway, best to stick with the safe side of things and email Dr S.
Hi Girls
This dial up is killing me...but I'm trying to keep up with everything. Our FS has recommended Colorado protocol too so I'm really interested to see how you find it...keep us all posted xxx
PP - i don't think it's a case of the local clinic wanting money but not taking responsibility for your cycle. they're not suggesting the use of the prednisone or clexhane so they can't really be responsible for telling you how to take it - that has to fall back on the doctor that has prescribed them. the local clinic can only do "their part" of the process - monitoring O for natural FET, and then arranging transfer - the additional medication has been recommended by Dr S so only he can say when to start it etc (and no, i'm not defending the clinic just because i see the same FS - would say the same to anyone!!)
re the treatment - i would contact dr s by phone if you're not getting an answer to your emails - i believe you've had AF visit and you're now looking to do a natural FET - the last thing you want to do is wait on the email and find that you've started the prednisone too late to be helpful this cycle....
good luck hun - and don't forget to call mac re the metformin XR script today!
I have received an email from both clinics and it is my FS in Melbourne that had prescribed the treatment so i am no longer needing to consult with DrS. i guess i just go along and don't change anything until someone tell me to.
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