IVF with PGD #7

I'm here!!! Good luck. Keep me/us posted!

hey .....day 4 of the lucron and im shocked how hard the shots are this time! im a wuss! shaking and shaking before i do it!!!
ive never been this bad before!
Also ANY one struggling with daylight savings???
I am super worried as I usually do my injections at 6am now (7am) before i leave for work at 6:30 so i cant do them at the old 6 am ill have to do it at the new 6am which is really 5am! does this make sense???? do you think thas its ok??? im only on day 4 of lucrin shots so i hope its ok to change and have an hours difference????????
and its a long week end so i cant call clinic crapola! unless i call the emergency number but ill look like an idiot!

I'm not sure Hun I always did mine at night. You won't look like an idiot tho :)
X

First blood tomoz....

Good luck!

Hey
Start FSH tomoz then more blood Monday!How r ugoing??

More bloods tomorrow".......getting better at jabbing!!!

Hows it going Lu?

Hey they collected 4 eggs ��3 were icsi and 2 fertilized now it's day 3 and I'm waiting anxiously for 3 day update

Oooh good luck!
That cycle seemed to take ages!
Hope your feeling well.

waiting for day 5 update!

FX Lu!

Not great news 2 of embryos have lost cells not sure what that means only one is an early blast and might be tested tomorrow morning won't know till then then wait some more for pgd results
How u hoing

Oh poo Lu. Well I'll be praying you get good news!

In good... Wondering where everyone else is?!?!

None made it to even test......shattered

Oh Lu. :( I'm so so so incredibly sorry. My heart is breaking for you :(

Take the time you need then come back and let us (me?) know how your doing.

xoxo

Hi there!

I'm new here, we are just starting the process of doing PGD IVF...

We already have a 3.5yo son who has inherited an X-Linked condition from me (i.e. I am a carrier but he is affected). We are doing PGD IVF to try and avoid the condition in our second child.

We've seen the Fertility Specialist and Genetist and also had our nurses and counsellor appt's with Genea. Next step is an appointment with the PGD Scientist before they start developing the genetic test for our family. So I guess we are still 2-3 months away from actually beginning IVF. We're still wrapping our heads around the science, and all the decisions we may have to make along the way.

In our case the specific gene causing the condition has not yet been identified, but they have narrowed it down to a small section of the X chromosome and identifying markers. Because of this we've been given a 95% chance of correctly identifying an affected embyro but not its not guaranteed.

There is still one thing I'm unclear on though (it may be come clear at our scientist appointment - I will certainly be asking the question there). Because we have an X-Linked condition, embryos have 3 outcomes : Affected (male, 25% chance), Carrier (female, 25% chance) or Unaffected (either, 50% chance). Obviously our hope is for unaffected embryos. However if we don't get any unaffected embryos I'm unsure whether we will have the option of using embryos which are carriers? And whether we would want to or not? Its been mentioned that it might not be our decision as it might against Genea policy to transfer an embryo which is a Carrier?

Does anyone else have experience in this sort of scenario? Any advice on what other kinds of questions I should ask the scientist?

Thanks!

Hi Redmonkey!

I'm also with Genea and I was allowed to use carriers, we didn't end up using one but we were allowed and still have one frozen with them.

Our situations are very similar, I also carry a X linked disease altho we were fortunate enough to know alot about it due to it being in my family for generations and diagnosed when by brother, now 27, was 6 months old. All my grandmothers brothers died as children but they never knew why. We are so lucky to live in this age of medical miracles, doing pgd was the best decision we ever made.

Do you mind me asking the effects of your sons condition?

Try not to get hung up on the 95% thing. Think of it as their 'get out of jail free card'. It's pretty much to cover their butts so they can't be sued if they do ever get it wrong.
I severely questioned them after our 3rd cycle when we had 7/7 unaffected. I accused them of getting it wrong as it was just to hard to believe but he basically said trust me it's right. As in, we don't make mistakes :b

As for the scientist appointment I would advise that you write down your questions and make sure you get answers you understand. Some of them tend to forget we don't understand science talk! It's like talking to Temperance Brennan from Bones LOL!

Considering our similar conditions and the fact that we are with the same clinic feel free to ask me ANY questions :D