IVF with PGD

WTH: Hope your appointment gave you some answers and helped to find a way forward.

Meredith: Thanks for you help with the questions, hope everythign goes well for your EPU tomorrow, will think of you.

Buliej: Thanks for your explanations, it really helped.

Cuddlepie: Perhaps have another think about PGD once you know the egg numbers, if it's eight, there shouldn't be a problem with doing it.

AFM: Just coming from appointment with my FS, we'll go with an antagonist cycle straight with my next period, which should be in 4 to 6 weeks.

Feeling a bit down at the moment, my FS pointed out that the better egg number that my scan showed in September 4 to 8 could have been an outlayer and the bad number with my last cycle (2) the normal thing, seriously hope that she is wrong.

Sara

Sara big :hug:, I hope your FS is wrong about the egg numbers but glad that you have decided the plan of attack for the new year. Did you get to ask all the questions you wrote down and are you happy with the decision?

Buliej, I found all these are so hard ATM, we need PGD due to our age and at the same time, due to our age, we have limited eggs...which way do we go? Hope you soon will find out the reason for Trisomy 15 is just a random luck...TBH, about your questions regarding CVS and testing, I haven't even contemplated that far yet but would love to know if anyone has answers.

Clinic just called, another tracking on Thursday which is what I expected and estimated EPU will be Sunday if all goes well. Seems that there are 7 follicles there and she said although not many in terms of size they are quite close together which is good. So best for me will be 7. Lucky 7 I hope. well, one thing I don't have to worry about is OHSS, E2 is 3645 which is consistant with number of follicles. More cooking to do for me...big sigh...

Late post today. Busy day and then worked late. Not so great given I'm still bit sore post EPU

Buliej - most trisomies especially the "lower" number eg 13, 15 16 etc will miscarry so would unlikely ever get to the point of testing via CVS, amnio. I will not be doing any further screening other than NT scan unless REALLY warranted as they all carry a risk of causing m/c. My FS agrees, saying that the majority of "abnormal" babies miscarry anyway and with my history of m/c, just wouldn't be worth the risk ( unless we got bad scan etc)

Sara - Glad you decided on antagonist cycle and praying it works well for you.

CP - At least all your follies are around the same size so all sjhould be "ripe" together. Hopefully thurs scan gives you a suprise with some extras!

WTH - thinking of you and hoping all went as well as can be expected at today's appt

Me - All 14 of our embies were suitable for biopsy today ! I am amazed!!. Nurse said the lab was going to be busy with my babies all day! ET at around 1pm tomorrow and will find out results of PGD testing when we get there. There's got to be some good ones out of 14 doesn't there?!

Meredith - that's fantastic news - it sounds like you will have a few you can transfer...and maybe freeze???

THERE HAS TO BE! Meredith! I am so thrilled for you, that's a great number and greater chance! I can't wait to hear the result hun and all the best for today's TR! I hope you will have half dozen at least make it to frostie town!

Meredith - that's wonderful news, they have to be good ones to all make it that far. Will be thinking of you - good luck with ET tomorrow.

Sara

I am a new member and felt I should join the chatting after reading all of your stories of TTC. Background on me: lost twins in 2005 at 10 weeks; had to terminate my sweet baby boy at 5 months due to genetic problems and a heart that was not complete-Aug. 2006; delivered a wonderful healthy baby boy October,2007. Now, just went through PGD and miscarried the only good embryo out of 12. I don't feel ready to give up, but not so sure that I have any good eggs left. I am waiting for my numbers to go back to zero before meeting w/FS. I was already told egg donor or adoption was my best choice, but would like to give PGD another shot. Just wanted you all to know, that I am walking down the same road as most of you. Sometimes feeling lost and hoping that I will find the right way.

Hi Kelly,

Just wanted to send you a quick welcome message.

Really sorry to hear that you had so many challenges on journey. Whishing you all the best with finding your way. When do you expect to be able to meet with FS?

Cuddlepie: good luck with BT& scan tomorrow

Meredith: hope all went well for you today and you are resting after ET.

Sara

Hi KellyQ - so sorry to hear how difficult trying to conceive again has been. The members here have been so helpful - answered my many questions, and shared their experiences - I've found this forum to be very helpful. Hope you do too.

kellyq - welcome aboard, you will find some wonderfully supportive women here. If you don't mind me asking, what condition did your son have? You may have read that I also terminated a son at 30 weeks.

Meredith - Well done, that is a great number to biopsy, you should get lots of bubcicles to freeze.

Cuddlepie - Hang in there sweetheart, buliej is right it is the quality not the quantity. Just try and stay positive, we can all agree that that is easier said than done but what more can you do.:hug:

I am going to indulge in some self-pitty now, today is the 6 month anniversary of my delivering Brendan, or precisely 9.40 this evening. The cemetary where his ashes are placed are having a Christmas Service on Friday evening so I am going to that. Not sure what I am expecting but I will certainly take alot of tissues. DH isn't coming with me, but that's OK we all want to deal with things differently. Tearing up, better go.

LisaK - what a tough day for you. I'm sure the Christmas service will be very special to you...and that you will need all the tissues. My thoughts will be with you.

Oh my God! I have just written the longest email to EVERYONE and managed to darn well lose it! I am fuming right now. I seriously spent half-an-hour on it and was ready to press "send". ARRRRRRRRRRRGGGGGGGGGGGHHHHHHHHHH I will be back soon when I have managed to cool off!!!!!!!!!!!! :rolleyes:

OK, I have regained my composure. This is basically what I wrote before I lost my last post...

Lisa - :comfort: What a strong woman you are. I really admire you for attending the service on your own. I guess we all deal with grief differently. My DH is the type who goes quiet and bottles things up. Maybe he is a little like yours?? I know not a day will go by that you do not miss Brendan but I do hope attending the church service helps gives you further strength to move forward

Buliej - you will be interested to know I got a script for DHEA! Will arrive about Friday and I can't wait to get started. My FS was not certain it would help me. He has some other clients on it and says it is generally given to women only produce one or two eggs in an IVF cycle. He says it definitely has shown to improve egg numbers, but that the jury is out on whether it improves quality. I also purchased some Maca Root powder this morning in the hope it might help with my estrogen in between IVF cycles (I know I cannot have it while on it). But now I am wondering if it will mess with the DHEA. The Maca Root is said to stimulate the pituatory gland and balance the LH, FSH, P4 and E2 hormones. Any thoughts??

Kelly - :welcome: Thank you for sharing your story. I am sorry about your recent MC after PGD. This is a very special thread with women who understand your journey, past and present. If it is of any help to you, the PGD scientist told me they recommend trying 3 PGD cycles before considering other options like egg donation.

Sara - :wtf: never even heard of this "outlayer" business, but who says it isn't the other way around. Maybe this was a freak dud cycle. After all, when my first cycle was cancelled many people on BB were quick to point out the first IVF is very experimental. Maybe you needed higher FSH or were oversuppressed by the Lucrin? I will be starting my Orgalutron cycle in about 4 weeks so looks like we are going to be cycle buddies :D

Cuddlepie - :goodluck: cooking your Lucky 7. I am sure you will do better than I did as my 7 were had what was considered a "big dropoff". You are very likely to get both a transfer and one or two frosties. Good luck with your next scan and BT

Meredith - Holy Moly - 14! :o I can't remember if you are doing Day 3 or Day 5. That's fantastic! Surely, it's a record. You have been through so much. I am so glad the cycle offers such high hopes for you. Just think, in two weeks you may be UTD. Now go on, give your tummy a rub from Aunty WTH

KMN and BW - thanks for thinking of me :)

AFM - FS decided to give Gonal F a whirl, next cycle. Same dose of 375, but he says it can be a little more potent. I am also about to start DHEA, at my insistance. Meanwhile FS thought it would be a good idea for DH and I to TTC naturally this cycle, given we managed a normal eggie last month (due to the stims, I believe) and the fact my up and coming follies have bathed in two months of stims. He was against a back-to-back cycle as he says in his experience, he sees lower follicle numbers. I am feeling fine despite the BFN. Got the next cycle booked, had a new cut and colour done today, have a few accupuncture sessions coming up and am starting to think about the BD marathon coming up in the next week or two :redface:

HI ladies,
I feel a bit awkward posting all my good news when so many of you lovely ladies have had such bad news lately but hopefully there will be some more good suff for everyome soon,
ET did go ahead today albeit although with some stress this morning after the lab called me wanting to know if we wanted to grow on to day 5 as we had a few to choose from. I am really not good at changing plans so was quite anxious about the whole "on the spot" decision but DH and I talked and decided to stick with today which we are now both happy with (will explain more).
Of our 14 biopsied embies, 9 tested "normal" and 5 abnormal so really a much better result than i expected for my age and history. Of those 9 , 5 had continued to grow on post biopsy and of those, 3 were at the compacting/morula stage expected for day 4. Our reasoning was that in another 24 hrs it was still going to be a choice amongst those 3 assuming at least 2 continued on, so I feel happier with them in me tha waiting the extra day. The lab does say they think there culture conditios are good enough to replicate the woman's body but I am not 100% convinced that all embies that fail to grow to day 5 would not have made it in their "natural" home.
Anyway, we now have 2 on board and praying at least one sticks for the long haul.
Not getting my hopes up for frosties but hoping at least the other morula makes it and there is a chance 1 or 2 of the remainig might catch up and make to freeze. Will find out in couple of days.Brings it home how much of a numbers game it all is.... started with 21 eggs then 14 embryos, then only 5 normals that also were developing and then really only 3 stand outs. I know it only takes 1 but it seems to need a lot to be lost to get that elusive 1.
Our 5 abnormal embies had varying combiations of extra or missing chromosomes, mostly for 16 and 22. NO downs ( 21) or a repeat of our trisomy 15 in any of the 14 embies. Interestingly, a few of the abnormal embies had continue to grow on to morula stage so actually doing as well/better than some of the "normals". Just shows that how an embryo looks under microscope doesn't actually mean how "good" it really is.
Sorry for the long winded post but basically, we are suprised( happy of course) at the great results so far. Now we just have to get pg ( and stay that way for 9 mths)!!


Kelly - welcome to this priceless group of women. I am so sorry for the tragedy you have already edured. I have lost 6 babies myself but the desire to keep trying hasn't eased yet. I pray that you can get sucess through PGD. There has to be a good one left in there somewhere!

Lisa - my thoughts are with you had this hard time. I hope you can get some comfort going to Brendan's resting place for the ceremony

CP - hoping all is going well with you too. Is your next scan tomorrow?

WTH - dooooh! Don't you hate computers sometimes! I see on your sig that you will be starting again very soon. Looking forward to hearing what your FS had to say

WTH - sorry, posted at same time. You are such a brave lady,picking yourself up and looking forward so quickly. Praying that you don't need the DHEA or increased GonalF as you will be UTD in a few weeks!! Don't answer if its to personal but have you hd any doubts about the financial burden of several PGD cycles? If this one fails for us, then i don't know if we can sensibly afford to do even another, let alone several, particulrly in a short time frame. Actually, we could do it and I would but don't think DH would agree especially with all the financial mess going on the world.
I find it really hard to deal with all the emotional stuff and still have to be "rational" with money.
Just wondered what others think?

Hello ladies, lots happening!

Meredith, don't you feel awkward at all of those result, enjoy it! You've been through so much and deserve everything finally coming right for you now. I hope the two in your tummy will be staying for the next 9 months. :D Its so interesting to read the stats and how the 'abnormal' ones continue to develop even more so than the normal ones. That does proves the purpose of PGD. You just can't tell otherwise.

I do understand that you need a big number like yours to filter them out and still left with some decent frosties. Would be anxious to know how many survived in a couple of days time. What a great cycle for you, I am truly happy for you and hope this is IT and you will never have to do this again!

WTH, glad to hear that you are sounding so positive, I bet the trip to hairdresser do the tricks as well, it can always pick me up. :D Enjoy the natual :bd:, sometimes I forget that's how 'normal' people make babies!

Sara, I agree with wTH, don't be disheartened by FS said 'outlayer', it is your VERY first cycle and they are just testing it out. You might get a pleasant surprise with a different approach.

Lisa, my heart goes out for you at this difficult time. 6 months, the pain must be still raw, indulge yourself during the service and hope you can feel the beautiful spirit of Brendan ....:comfort:

Welcome Kelly, so sorry to hear your hard journey so far, I am sure you will find some comfort in BB, girls here are not only compassionate but resourceful...hope soon your dream will come true.

AFM, feeling good these couple of days, no sickness and pretty much no side effect. I have been doing beautifully with the self-injections without DH at home. So, proud of myself...:p

B/t and u/s tomorrow morning, hopefully by afternoon, I will know the trigger time. Hope it will be Friday when DH is home.

Have a good evening everyone, early start for me tomorrow so going to head to bed...

Meredith, I can understand the financial burden with the current GFC (global Financial Crisis, they even give it a name) looming...there are lot of uncertainty with job security and everything. I know you have a little one to care for so not sure if you are working full time. So DH must be the main bread earner, I can sort of understand where he comes from...

I know its hard when you are going through an emotional hell trying to achieve your dream but then there is this hard cold money issue to consider. It just doesn't go together. I guess its the balance how you can make it work. To us, its an easy decision because we haven't got any kids yet so we probably will keep going until I am officially over the hill. But if I do have a child(ren) already, I might re-assess my priority if financially becomes difficult because I would want the existing family to come first, at least in the short time frame.

I hope you won't have to make any decision Meredith because this cycle you will be pregnant anyway...but its a hard call I'd say...

CP - Thanks for your thoughts! Glad you are doing well on your own and hoping DH can do your final jab for you! GL tomorrow... grow follies, grow!!
Re the money, I only work 1-2 days a week as I really want to be home with DS but I do understand the extra pressure that places on DH. I guess, really,we are fortunate to be in a position to do IVF/PGD at all. I am sure there are plenty of couples out there needing treatment to achieve a dream of family life, yet totally unable to pay for it. Just doesn't seem fair..... none of it!
I forget that it costs the majority of people zilch to actually get pg! ( oh except maybe a couple of glasses of wine.... heh...heh!)

WTH - congrats on obtaining the DHEA script - I'd be very interested in hearing how it goes (assuming you need it) - please keep us posted! I spoke to my FS today and she doesn't think it's for me (which didn't come as much of a surprise) and to be honest, I'm not that upset about it - she gave reasons, which jive with my readings (according to her, I'm not a poor responder and I don't have ovarian failure (what a horrid phrase)). I do think that research over the next few years may show that DHEA is good for older women generally - but who knows...and I may push the issue should I go through a few more cycles with BFNs or worse (more m/c). I did some Plan B research and have the names of dr's who prescribe things like DHEA - so I'll keep that in my back pocket. Also, I can tell you that I did back-to-back cycles at my instance - my FS warned me that these usually don't work well - and she was right - 3/4 embryos made it my first cycle and 0/3 embryos made it my 2nd (the back-to-back) - so I think a month off with TTC naturally, if that's an option, is good advice (based on nothing more than my own experience). I'm due for color on Friday (can't fit me in for a cut until Jan!!!) and a massage during my lunch break tomorrow - I'm being rather good to myself and DH is being great about it.

MeredithD - I LOVE hearing good news!! I find it gives me so much hope. Your numbers are fantastic - I so hope that you end up with a BFP and then a H&H in 9 months. Meredith - would you mind repeating your history- as I too had the trisomy 15...and are now awaiting results of our genetic testing - I'm very interested in hearing what you learned about yourself and your DH in terms of genetics and whether the other abnormalities are spontaneous or genetic. I am really struggling whether to try a few more cycles without PGD or whether to go through PGD - given that I can't expect to get much more than 4 eggs, this is a tough decision.

about the $ - that's such a hard decision and so personal. I personally think that I'd be similar to Cuddlepie in my thinking, as we too don't have any children yet...but I've also learned that until you are standing in the shoes of someone in a particular situation, there's really no way of knowing what you'd do. I think the most important thing is for both you and DH to be comfortable with your decisions as there's no right answer. Sometimes I think about what this would cost us in the US and I'm so thankful that we have chosen to make Melb home...but this is particular to me and probably won't make many people feel that much better (and sometimes I wonder whether I'd have more success in NY...but that's a whole other story and, when I'm being rational, most likely not the case).

Hi to everyone else!

Good morning all, a little report of my scan to my BB support team...:p

Not as dissappointed as I know what I'd expect, so follicles are growing nicely, the biggest one is 21mm, there are two smaller ones popped up (11mm & 13mm) but I don't know whether they will be big enough to have mature eggs in them by the time of EPU. Anyway, will see.

My lining is a bit thin 6mm ATM, do you guys think that it will be a problem for TF? I thought normally it should be around 8-9mm at D11. Well, at least they can do EPU that's all I care about.

Have a feeling that trigger will more likely to be Friday...

Hope everyone will have a good day!

Cuddlepie - I hope things progress smoothly (I don't know much about linings) - if your trigger is Friday is your pick-up Saturday?

Thanks Buliej....if trigger is Friday, trigger will be on Sunday...so hopefully I can get it done and over with this weekend....:p

Hi,

Just wanted to quickly drop in and wishing you all a great day.

Meredith: It's great to hear you're good news.

Cuddlepie: Good to hear you're feeling better, keeping fingers crossed and thinking of you.

WTH - Great you're having a new plan, please keep us up-to-date on how you're going with the DHEA - if my low egg number are repeated it may be the way to go for me too. Did you get the script from your FS at SIVF?

Sara

Thanks ladies for all your warm thoughts and cyber hugs, I really appreciate it.

And yes, DH is a bit of a bottler (new word) but he has his moments when he lets things go, so maybe a happy blend for him.

Meredith - Your good news is wonderful to hear, if we can have happy times vicariously through you then that's great. I wish you only the best and we need a baby here.

yeah I agree....we need a BFP and :baby: here, starting with you Meredith....

I would like to thank all of you for the encouraging words and caring thoughts. I received my blood work today and was at 750. I was hoping for a zero so I could move on, but now I have to go back for a repeat BT next week. I really don't want a D&C.

This past PGD cycle they retrieved 12 eggs, 10 fertilized and 8 were able to be tested for 12 chromosomes. All had multiple trisomies and monosomies except the one which was deemed "normal". I was surprised that only one was good- so was the FS.


LisaK- I know how you feel and your sadness for the loss of sweet baby Brendan will always be with you. When I lost my baby Benjamin (trisomy 21 and a broken heart), I had a dark cloud around me for a long time. I wonder if my pain and grief only make me appreciate what I have now, more. I will be thinking of you and hoping that the sun will shine through for you.

Meredith- I am in the same $ boat as you. I am hoping to do PGD again, but with a price tag of $6,000- this will be my last time. I am keeping my fingers crossed that you will not need to go through another cycle. C'mon baby...babies!

To all- I am trying to get all the lingo down. Lots to learn! I am still leaning how to text! Buliej- not so sure what FET is. You all sound like you could hold a lecture on IVF and PGD. I am a novice!
Good thoughts sent to all of you.

~Kelly

me- 39 DH(dear husband??) 56

PS- WTH... I had to write this twice- I lost the first one,too!! AHHH!!!

Cuddlepie - I want to see two BFP before Christmas :)

Lisa: I am sorry only now saw your post from yesterday, this must be so hard. Hope the Christmas Service gives you some peace. :comfort:

Kelly: Hope your next BT gives you the result you want.

Sara

That's funny you think I could hold a lecture whereas I feel I know so little. After my 12th question to my FS yesterday, I said "sorry for all the questions, but I've never known so little about something so important to me". She was actually very kind and said "ask away" and to call her if I come up with more.

A lot of what I've learned is from the ladies on bellybelly...and I'm am obsessive google-er - but with the internet, you can never be sure of the quality of the information - often I take it and bring it back here to bellybelly to see what others know. Sometimes, when I'm exhausted from all my reading and the decisions that need to be made, I wish I was the type of person who could just sit back and let this happen and let the doctors make all the decisions - but that's not me...

...and FET is frozen embryo transfer - somewhere on bellybelly is a post with all the abbreviations - I knew none of them when I started this process in Sept!

Instead of singing 'chicken tonight' I am singing 'Trigger Tonight', in the bid to calm the stressed-self down...

I didn't get the call from clinic until 3ish this afternoon and I was totally expecting to do another scan tomorrow and trigger tomorrow night, which would be perfect because DH will be home to put the needle in my bum! So when I heard 'trigger tonight at 730pm, I totally freaked out'. Then there is logistic things to sort out. Leave work early to pick up the trigger, cancel tonight's Xmas party plan and have to move Saturday engagement to another day. And of course tonight, I will have to inject myself in the tummy, what can I do but to bite the bullet!

Well well well, my egg-growing business has almost done and now time to prepare laying them on Saturday, wish me luck!

Cuddlepie - best of luck - I hope you drop a lot of strong, healthy eggs!

CP - Guess you would have done trigger by now. Hope it all went well and you are looking forward too "drug free" day tomorrow. Go those good little eggies!! RE your lining. I always have issues with mine but have fallen pg many a time with around 6mm on day of trigger, my DS was one of those times. I asked the Dr doing my ET the other day about lining and she said the actual thickness is not as important as whether it has grown since your first scan.

Buliej - My history in a nutshell is that I have had 5 pregnancies in the past 4yrs, all but one concieved with OI/IUI. Of those 5, only 1 made it producing my DS. We had chromosome testing on all my m/c's ( except the first)... 1 normal girl, 1 boy with trisomy 15, 1 normal boy and 2 other babies ( the "other" twins from my last 2 pgs) with no result. DH and I tested normal so my trisomy was just random. My PGD results also seem to just reflect the random "expected" trisomies/monosomies for someone in my age bracket, however the PGD scientist did say that each cycle can be quite different and we'll never know if this was a "good" one for us.
I can certainly understand the fear of doing PGD with only small no's of embies. Its a hard call but I have kind of said to myself that if the embies can withstand the PGD then they are probably the strongest anyway. Its impossible to know if the 4 "normal" embies we had that failed to grow on after the PGD, would have failed anyway.

Lisa - thankyou for the well wishes. I hope I can bring some hope that PGD works... please let it work!!

Kelly - what tough stats with your PGD cycle. I truly hope that was just a "bad" month. At least you know you CAN produce a good embie. Its just gotta stick!!
I am soo sorry your HCG is not falling. All my m/cs have been a bit of nightmare in this regard. My most recent, i had 2 D&C and still took 12 weeks for my lvels to reach zero. I was desperate to try again but I guess now in hindsight, maybe it was for the best to be forced to let my body rest and recover.

AFM - Not much to report, just feeling anxious already about this 2ww. My BT will be on 15/12 - seems so far away! Should find out tomorrow if I have any bubbies in the freezer

Thanks Meredith for easing my mind a bit regarding the thickness of the lining...yeah, done the trigger now and looking forward to the drug free tomorrow. Have AP though, so still can't escape needles...

Looking through the conversations between you and buliej about the stats, just feel that even with such an advanced technology these days, there are still so many questions that no one really can answer. There are lot of 'luck', 'chance', 'random' and 'nature's desire' really. For some of the things, we might never have answer. This is actually the beauty of life, there is always something unknow, unable to calculate, left you to hope and wonder.

After all the scientific facts and logical thoughts, I do believe that universal sometimes choose the timing for us and I do like the thought of 'miracle does happen'.

Meredith, I think this is YOUR time and the little miracle is growing inside of you at this minute.

*pardon my drug-talk* - this must have trigged sth. else in me...:lol:

Meredith - thanks for sharing your history. I was wondering if the chromosomal issues were all spontaneous - I guess I'm getting a sense of the issues with age - it's taken a while but it is sinking in that they extend beyond just trying to get the BFP and that the genetic testing being done on DH & I is not the be all and end all in terms of answers. You've given me good stuff to think about (I mean that - you've given me a factual context which is really helpful) ...for better or worse, DH and I have some time to mull this over. I look forward to your BT results...BFP before the new year!

CP - enjoy your drug free day - let us know how the pick up goes...will DH be home to go with you? It's frustrating for me that there's a huge "unknown" factor with all of this - but it's not a surprise - creating a life is indeed a miracle! I just hope to be able to participate in it one day.

Wow guys, this is a really helpful discussion, it's really a very special forum.

Cuddlepie: Just wanted to wish you lots of luck for the pick-up - perhaps you're getting a happy surprise.

Meredith: Hope you will get some embies in the freezer - but you know, you won't need them anyway, this is definitely your time! Go the Christmas BFP.

Sara

Cuddlepie :D - just want to send you a big cheery :goodluck: for EPU tomorrow. I hope you have an excellent haul of some lovely eggies. Will be thinking of you.

WTH x

Hi all

I havent written in before but spend every night checking on you all - it gives me the courage to keep going.
We have been TTC since Dec 2006 (Me 38 DH 39) and had first IVF cycle in May 08 for unexplained infertility. We were excited with BFP first time. However at 12 weeks found out we had a trisomy 21 pregnancy which we terminated and have regretted ever since. Unlike you all I was one of the 10% who didnt miscarry and really dont know what is worse. We have PGD this cycle and had 4 of our 7 frosties tested as well as the 2 good ones from this cycle. In TWW as we speak had the only frostie that tested OK transferred. HPT was +ve but very nervous about BT tomorrow. In answer hope we to all those questioning whether to have PGD think long and hard about what you will do if you get the test results we did at 12 weeks as after 3 'normal' scans it was the biggest shock of my life.
Wishing you all well and will have m fingers crossed in cyber space for you all

Ishy

HI ladies, need to vent tonight as feeling bit flat. Found out today that none of our embies made it to freeze. Couldn't get much more detail other than that they had started to degenerate by today. Not sure if they grew on past day4 but I guess maybe they did given they kept them going until today (day 6). I had told myself I souldn't expect any frosties but did really think we would at least get the 1 that looked good on day 4. NOw I am really worried about the ones that were transferred as they were about the same quality as that 1. Maybe they are already gone?
Trying to stay positive in the hope they they were the only good ones but its hard when so many supposedly "good" ones have just failed to develop
There is SOOOOO much more to this baby making than just "normal" embies!!
My one consolation at this point is our decision to transfer at day4. Maybe they will fair better in me... Hoping so! Sorry about the whinge. I know I should be very grateful we even got any to put back.

CP - Just as ou said, there are so many unanswered questions about TTC. Every child is such a miracle of nature.
Wishing you heaps of luck for tomorrow. Go those lovely eggies!

Buliej - Glad to be of some help. Its so hard with all the decisions we face. I am like you, can't help myself researching every little detail but then it just stresses me out. Ignorance and blind faith in Drs really would be bliss sometimes but sadly doesn't always get us the best treatment. These days I think you really need to be informed and push the Drs on everything. I think IVF is sometimes to much of a "sausage factory" and you need to ask to get "out of the box" care.

WTH - hope you are doing ok. I know you have been worried about your big "drop off" from 7 original embies but my figures are very similar 14 embies down to 2-3 supposedly "good" ones although don't know if any would have actually made it to blast. My lab didn't seem to think this was that abnormal. I find it odd I must admit given both of us have seemed to get pg without excessive difficulty in the past so we must have had plenty of embies develop just fine.
I don't know but maybe some people just make embies that can't hack it in the lab?

Ishy - I am so sorry for your loss. What an awful decision you had to make. A positive HPT is a positive so I would say you are UTD... yipee!! Best of luck with BT tomorrow!

Meredith, remember that your embryos are INSIDE YOU. Totally different environment to the lab, and honestly the best place for them. Have faith in your embryos and your body (as hard as I know that is), that they are at home and snuggling in for the long haul. I can imagine your disappointment, but time to focus on what you have right now - two very real chances at a healthy baby, and all the drugs under the sun to help them stay with you. Hang in there! :hug:

Cuddlepie, good luck with EPU! Will be awaiting results with interest.

BW

Thanks BW... hope you are right. Guess I just wanted a frostie or 2 as a saftey blanket. Please don't let me need any!!!

Will be praying like mad for the duration, Meredith. Just know that while you are the one doing the hard part of things, you aren't alone as you journey through this.

BW