IVF with PGD

Meredith - I think you can't compare your body to a lab - I think the 2 inside you have a great chance of giving you a BFP and a H&H baby. At the end of day, a lab is a lab - they don't understand everything about a woman's body so how could the possibly replicate it no matter how good they are.

Cuddlepie - good luck with pick up

Ishy - I hope the BT gives you the definitive BFP that you deserve (please let us know - we'd be so excited for you). You had to make a horrible decision....gosh, the more I info I have from these posts the more I think that PGD is the way to go and if it means multiple cycles to get a good embryo - so be it...I don't want to miscarry again nor do I want to be faced with the same type of decision you had to make even knowing that we'd do the same...but it would be heartbreaking.

WTH - Hi...hope all is going well.

Hi,

Hope you're all having a nice and relaxing weekend, glorious day down here.

Meredith: I am sorry to hear you had bad news about your frosties but definitely agree with everyone else that the lab is a much tougher environment for your embies than to nest in their natural environment, try to hang in there I am praying things go well for you.

Cuddlepie: Hope you had good news and are resting comfortably after EPU. Have been thinking of you this morning,

Ishy: Welcome to this forum, I am really sad reading your story as it's similar to my own, it's one of the hardest things that can ever happen to you. Let us know how your BT goes.

BW: It's good to hear from you, hope all is well.

Buliej: Have a great birthday!

WTH: Cyclebuddy hope the DHEA does wonders for you. I was on Gonal F last cycle, the needle is really fine and didn't hurt at all.

AFM Already nervious about the next cycle. My FS said she'll start me on 300, wondering if she shouldn't go a bit more aggressive from the start, last time I was on 262.5 from the start and then went up to 375 without any effect. Anyway perhaps may have to insist on an early BT and then to get really more aggressive if E2 number are not up.

Sara

Sara - quick note - I think you should ask your FS about the dosage just so you understand why they are picking that level. I don't know much about dosage except for my own experience first flare cycle - started at 350 gonal f - after first follicle scan she pushed up to 450...2nd flare cycle - she started me at 450 ...3rd cycle which I hope to begin in Jan and will be antagonist, script again says 450. It may be that if you get good results from lower dosage, they don't want to give you unnecessary hormones. However, it was my understanding that they start low so that you don't get OHSS (or whatever the acronym is over having too many follicles) but that this is not really a risk with older women.

WTH - the gonal f needles didn't bother me at all - found it very easy to do - didn't even feel the needle, when the medicine goes in it burns a tiny bit, but nothing too bad. I even thought I'd want my husband to do it, but ended up finding it easy to do myself. did you get a dvd from the chemist? it's handy to watch before you do the first shot. if not, the little pamphlet that they give you is helpful (if you didn't get that, I'm sure if you google gonal f along with the name of the drug manufacturer their website will have a copy of the pamphlet).

Hi to everyone else

Hi all

over the moon BFP- makes it worthwhile for a healthy emby to be transferred. I will keep watching you all- and hope I dont need to return after 12 week BT and scan:dance:

Have a restful weekend


ishy

ishy - that's fantastic - congrats

Hi everyone. Hope you are all enjoying your weekends, thus far:

Buliej - thanks for the tips on Gonal-F. Is it not just like the Puregon Pen? I guess what I am most interested in is whether it actually IS stronger than Puregon. My response to Puregon was reasonable. According to my FS, trying Gonal-F could be for better or worse. Have you heard if Gonal-F is better? I have been told they are both FSH, but there are "more sugars" in Gonal-F, whatever that all means....

Sara - are you switching to Puregon? I am REALLY surprised by how much your FS is holding back on your next cycle. My first Puregon cycle, I started on 200, was upped to 300. Cancelled, and next cycle put on 375. It is true that you can have too much FSH and sacrifice egg quality. But it does seem very conservative. Any chance of a second opinion? Do you feel confident at perhaps questioning this?

Ishy - sorry for your sad loss and what you have had to endure, but..... :dance: CONGRATULATIONS :dance: on your BFP :clap: Some of the ladies here have had to make similar difficult decisions in the past so they understand what you have been through. Just like you, that is what brought them to PGD. You are the first official BFP on this thread and give us all such hope. Wishing you a happy and healthy pregnancy :D

BW - :hello:

Cuddlepie - hope everything went okay with the EPU and you are taking it very easy. I had to giggle when you referred to the way "normal" people make babies. Not overly confident with the idea and scared s%@tless in some respects. Trust me, it has been a while! Might help me work off a bit of pudge I have put on in the past two months of stims, if nothing else...

Meredith - thinking of you and your lovely little beans nestling into there new home :crossfingers:

Lisa - hope you are doing okay, hon ;)

AFM - I'm fine. Meeting with the clinic Tuesday to organise paperwork for NY cycle :D

Hi everyone, I logged off early last night and wow there are a lot to catch up now...

Meredith, I am sorry to hear that there is no frostie and totally related to the 'safety blanket' thinking, a bit of battling here already and a bit scared of next few days to come really...focus on the two you have in your tummy right now, I sincerely hope that you don't need any frosties hun!

WTH and Sara, glad the new cycle is on horizon, something to looking forward to in the new year hey. I am sure the new year will bring some new energy for all of us.

Sara, I hope FS is monitoring you closely so if the respond is not as desired she can adjust straight away. To my understanding, no Lucrin this cycle right, so that's an factor could make the difference from the last cycle.

Ishy, so glad you had your BFP after a hard journey, you totally deserved this! Enjoy the excitement and hope this is the first one in this thread and Meredith will be the next.

Hi to BW and Buliej, thanks for thinking of me.

I feel relieved that the worst part of a stim cycle is over, at least physically. EPU this morning went really well we were back home before 11am, I have been drugged up to take the edge of the pain and had been sleeping a lot until now. I did saw some blood during the procedure, had one glimpse of the tube of fluid from my follicles and quickly moved my eyes away from them...I prefer to ignore them than freaked out. No bleeding afterward which is good. Pain relief worked well and I feel quite pain-free at the moment.

We've got 9 eggs, 2 immature, so 7 really as I predicted. Embryologist did say that they will still put all of them including the 2 immature ones for fertilization in hope that they will grow in the mean time. So we will hear what's the fert report tomorrow morning.

It will be interesting to see this cycle how many blasties we ended up with comparing to last two cycle. Assuming it was DH's sperm DNA affected past results, now with the improvement in this parameter, we are hoping to see some difference. I truly hope that this is just that little tweak does the trick. Thanks for all the support, I really can't do it without you guys..now the real torture of the mind begins...hehe

Enjoy the weekend everyone...

Cuddlepie: well done! Lucky 7 - sending lots of good thoughts to your embies. Take it easy hon and try to relax as much as you can to recover.

Sara

Cuddlepie - 7 sounds great! Just curious - where you not under anesthesia during the pick up ... it's sounds like you were fully awake - I've always been knocked out (they say light anesthesia - but I'm completely gone).

WTH - I've never used Puregon, only Gonal F - so can't speak as to the difference...I'm not sure if there is a "stronger" - my guess is that people respond differently to different drugs even if they are mostly similar drugs...just another one of those IVF things that seem so variable

Looks like there will be a few of us starting afresh in January - hopefully it will be a lucky month...I do hope AF arrives for me in the next 2 weeks - if it doesn't that will really throw me for a loop.

Buliej & WtH - I am absolutely sure that January is a very lucky month!

You got me confused I always thought Gonal F is Puregon - but now checked in the fridge and it said Follitrophin alfa or similar.

WTH I think it might be a good idea for me to use the other drug instead since I didn't react at all on Gonal F - it's probably different from person to person. I thought there was nothing wrong with your reaction on the other drug in the second cycle. But I think in these things we may just have to trust our FS, I have decided to go with what she says for the start but to insist on an early BT/US if they don't plan that anyway and if my FSH is not up to scratch to question if my dosage shouldn't be increased straight away.

Buliej: My nurse told me if AF doesn't come as expected to come in for a BT as they would be able to tell me where I am up - if you're nervous about AF, maybe check if you could do a BT, it might give you some more security. I've decided to go shortly before Christmas or in between the Years just to see how I am going as my clinic will be closed on Christmas Day and New Years Day and we want to go to the mountains for two nights over New Years Eve, would be a real pain if AF decided to come on one of those days.

Cuddlepie: yes there won't be any Lucrin and I am not on the pill so should be start with my normal hormones which hopefully makes all the difference. Hope you're still relaxing and enjoy having DH around - he may have to make fruit juices for you ;)
Do you have a few days off (I thought you said that you did with your other cycles) or is it straight back to work on Monday?

Ishy: Congratulations, that's really wonderful! Thanks for letting us know we need a few BFP here. :cheer: :bfp: :bluecheer:

Meredith: Hope you feeling better.

Lisa: Hope you're okay.

A nice Sunday to everyone

Sara

Sara, puregon and gonal F are essentially the same drug, just made my two different companies. There may be slight differences because some people respond better to one than the other, but they essentially serve the same purpose.

BW

Thank you BW. It's great to have you here. Hope you're going okay, a bit worried by your "in pain "status. It must be getting close for you.

Sara

6 weeks left... dealing with the joys of back pain and sore and swollen feet. It's all good though, I get to meet the little fella causing all of this very soon!

BW

Just a quick one, my ladies...

Fertilization report this morning showing that 6 of our eggs are fertilized. So out of 7 mature eggs, I think that's right on par with our fert stat (80%) :D the crunching time will be from Day3-5 though, fingers crossed. I am praying so hard that we will get more blasties than before....

Buliej, Im with SIVF, they do sedation first and then local anesthetic, so yes, I am awake the whole time, just feeling dizzy in the head like you are drunk, it was actually really good. I can look at the screen to see the needle going in to suck all the fluid out and then can see the eggs showing on the screen, its pretty cool. And doesn't take me long to recover afterwards. I think this is general practice in SIVF unless you ask for a general....

Sara, I am hoping to go back to work tomorrow. I was on painkillers yesterday but none today and feeling ok. I thinking going back to work just make time go faster IYKWIM...

BW, 6 weeks to go, good luck hun!

Big hello to Meredith, WTH, Lisa and Ishy.

Hope everyone is having a good Sunday.

You're doing fantastically, Cuddlepie! Well done! Here's to all 6 embryos growing well over the next few days and a trouble-free transfer.

BW

cuddlepie - those numbers sound really good - fingers crossed that they keep going and get A+'s on their tests! I may ask about the light sedation - I hate the time they make you spend in recovery after anesthesia - I'd like to avoid that and also wouldn't mind seeing what is going on.

Butterfly Warrior - so exciting for you.

Good idea Sara - if no AF by say the 18th - I may ask for a test to make sure my pregnancy hormones are back to 0 as they should be.

Cuddlepie: that's fantastic. Keeping fingers crossed the little embies keep growing.

BW: a summer baby, lucky you, hope your last six weeks just fly by. My sister ate lots of asparagus in in the last few weeks, her theory was that it helps release the water from the feet.

Sara

You guys have been really chatting this w/e. Haven't had any time to pop in until now.

CP - great job on getting 6 lovely embies. Praying you get at least half that in good blasties. I was right out for my EPU to but would find it really interesting to see what goes on.

Ishy - A BFP, thats fabulous news. Hoping you have a trouble free pregnancy!

Sara - I would say that your FS put you on a conservative dose because you are doing antagonist cycle so no supression at all. And as BW has said, Gonal F and Puregon are both exactly the same thing (FSH) just different makers. The general theory is that you should really respond to both just the same but it does seem different in certain individuals, Interestingly, my clinic told me that puregon is actually slightly "stronger" than gonalF. I was written up for 225iu of GonalF but since I'd used Puregon every other IUI cycle, they just changed to puregon but dropped dose to 200.

WTH - You might be interested in what I just wrote to sara about GonalF vs Puregon. Is just what my clinic told me but who knows? I really hope you have some "fun" over xmas and don't need your next PGD cycle

BW - wow, only 6 weeks to go. Counting down the days yet? I bet you can't wait to meet your precious little bundle

AFM - still feeling a bit disheartened by this whole thing although trying to have hope. I truly don't know what we will do if I don't fall pg. Not sure if DH will let us part with the $$$ for another PGD cycle but I am a touch scared about going back to "blind" OI/IUI's. Only 1 more week to go until BT. This part of the TWW really, really drags!

Just want to send you some hugs Meredith, i know this part of TWW is torture. Hope you are able to stay positive.

Hi to everyone on a Monday, I am on low key ATM...:rolleyes:

Cuddlepie & Meredith. Some hugs to both of you, the waiting game is terrible. :grouphug:

We're all here to support you and cheer on those Christmas BFPs :pray:

Meredith: thanks for the tips on Puregon - my FS doesnt' seem to give any instrutions to the nurses about which of them I am using, so may ask about Puregon next time, especially as a had a bad headache with the higher dosage of the Gonal F.

AFM: Probably still really innocent in this whole experience. Just really realised this weekend how stressful cycling is, really felt like my energy was coming back and that things that were in the too hard basket when I was jabbing are easy now.

Sara

CUDDLEPIE - :clap: congratulations :clap: That is an excellent fertilisation rate. You will surely have a decent number of blasts to biopsy :D

MEREDITH - hang in there hon'. You are a wonderfully fertile woman with every chance you will be officially UTD in a few days time ;)

SARA, LISA, BULIEJ, ISHY - :hello:

AFM - somehow managed to wake up with a UTI this morning. On antibiotics. Ho hum...:rolleyes:

Evening ladies

CP - thinking of you atm. I know these next few days will be stressful. Praying you have a strong and healthy bunch of embies growing in their dishes!

Sara - I get you on the stress thing. It is really hard to functions normally when you are pumped full of hormones plus all the anxiety over what is or isn't going on. Ah would be the joy to be one of those women who just finds out they are pg at 12-16w and everything is all fine and dandy. hard to believe they exist but there are certainly plenty out there!

WTH - thanks for the cheer. Wish I just knew already!

Realistically, I am either pg or not by now so just want to move on either way.... sigh.... I am normally very patient but not with this stuff!
Can't say I have a strong feeling for yay or nay yet. Got all sorts of symptoms but with all the drugs, who knows?! Pessaries don't usually stop AF so will certainly know by Saturday when she's due.

Sorry for being a bit slack ATM, haven't been feeling very well yesterday. I was sure that I am ok to be at work given I didn't take any painkiller on Sunday and feeling alright, but it turns out to be the longest day ever. At the end of it, I had bad back pain and felt a bit heavy at lower abdominal area. Didn't have a good sleep and still in crap crap mood today. I am suspecting because of the sudden drop of the hormornes...This morning, got a faint brownish discharge (sorry TMI) and maybe the old blood from the procedure just came out? Back pain is still here and I will see how I can stand at work today.

I had a good old rant to DH last night and think I just can't deal with all these anymore...anyway, today is a new day. I will update you how we go on the embie report later.

Thanks Sara, Meredith and WTH for thining of me. How can I do it without you? Sometimes it just seems hard. Meredith, I hope you are holding on alright, at this stage, no news is good news I guess. When is b/t?

Hang in there, CP. Any blood at this stage is likely to be from the EPU and nothing else. When's transfer and how are the little ones growing?

Meredith, also thinking of you and hoping you can maintain some sanity at this stage. Can't be much longer to wait now. :hug:

BW

Hi ladies,

Lying in bed with a headcold today so feeling pretty ordinary....

Buliej, Sara69, WHT - Thanks for your Hi, nice to be thought of, I am doing OK

Ishy - Welcome and congratulations with your BFP:dance:

Meredeth - Try to focus on the beautiful little person growing in your tummy, it is a lot happier in mummy than in a cold ivf lab.

Cuddlepie - Keep up the good work, 6 fertilised is a great number. Hang in there.


I went to the Christmas service on Friday night, it was really lovely and really sad. We were given a gift box that we wrote our loved ones name on and then hung it on their giant tree, and we took them home afterwards. It is now on our tree here. It is wonderful how strangers unite when they have something in common, I was sitting at the front on the end of the pew so everyone had to walk past me to hang their box on the tree, I was crying and I had 2 women touch my shoulder and offer me their sympathies, and another lady took my hand and smile. I cried lots that night but was really happy I went.

Have a good Tuesday and be kind to yourselves.

Thanks BW for the reassurance. Transfer is on Thursday.

Clinic just called about my 6 fertilized embies. 2x7cells, 1x6cells, 1x5cells, 1x4cells. So total 5 are still vaiable and two are a bit slow. I hope they will catch up soon.

This is the time that I wish that my clinic will just do Day3 transfer. Then I will have more to freeze etc etc. I know from D3 to D5 will have a big drop, with my spirit at the moment, I will feel very lucky to have a good blastie to go in on Thursday.

Lisa, I am so glad to read that you enjoyed the service and it must be beautiful and I have tears in my eyes. Have a good cry and grief your angel and I hope you find it make it a bit easier during this silly season.

Lisa - glad you found the Xmas service comforting - it's amazing how much the kindness of strangers can mean.

CP - those numbers sound good to me - as I'm new to the whole PGD thing - when will they test the embryos? isn't that why they can't do the day 3 transfer or can some clinics do PGD early enough so that you can still do a 3 day transfer?

Buliej, because this is our first cycle with my FS, he wants to see how many embies we ended up with for this cycle, so this cycle we won't be doing PGD. FS suggest it because of my age and past m/c, but only when we have sufficient embies....so obviously there is not enough and we can't risk with no embie go to TF. Tough tough tough....:rolleyes:

I think it is a general practice in SIVF to do 5 day embyros including PGD biopsy on Day 5. but I think in Melbourne, some clinics do Day3 biopsy which is what Meredith did....

Hi y'all

Cuddlepie - Just wanna give you a :hug: for feeling crappo. But.... at least your embies are doing wonderfully. In two days you will surely be PUPO (te he he - you taught me that one). I hope your back pain has subsided and you are getting some sleep. OMG - tell me about the hormones jumpin' and a slumpin' :o But there's nothing like a good ol' rant, eh?! Not long to go, now. :crossfingers: for Thursday

Sara - hiya potential cycle buddie. Have mean't to chat to you a bit about DHEA. According to my FS, you are the perfect candidate. Feel free to fire any questions my way.

Meredith - thanks for the info on the Gonal-F. I met with my clinic nurse this morning and fished for more info about it v's Puregon. Apparently my FS is swapping a lot of clients across at the moment. She says it is still pure FSH so I should respond similarly. I guess we will find out in a month's time... :pray: for you and your little beanies

Buliej - hope AF comes a knockin' real soon for you so you can get back on track ;)

Lisa - the service sounds very healing. It is lovely those women reached out to you (in only a way that women can). I am glad you are finding some much needed support in all corners. Seems very timely :)

BW - Oh wise one. Thanks for continuing to support the women on this thread!

AFM - surprisingly perky! Wasn't expecting to do so well after a failed IVF cycle! Perhaps it's knowing that I only have to wait one month until I start stims, rather than unnecessarily blowing one with the down-reg protocol. Have bought some fresh pineapple for DH to make his swimmers happy for proposed BD-ing this weekend :redface: Meanwhile, antibiotics kicked in right away so seem to have nipped the UTI in the bud. Was assured the drugs were Class A and would not interfere with my follies. Am on Day 8 now and usually have my estrogen dip bleed/cramps today or tomorrow. :pray: the MacaRoot/accupuncture/two months of stims do the trick and I make it through!

CP - big hugs to you atm. I can certainly understand your mood..... the things we put ourselves through eh? Sounds like your embies are on track for day3 but I know the next 2 days will be the real test. I am kind of with you on the whole day5 thing. I KNOW its meant to be gold standard and helps weed out the best embies, gives the highest pg rates etc etc but I just don't believe that every emby that didn' t make it to day5 would not have made it full stop. My sister did IVF 12 yrs and 5yrs ago ( that one with donor eggs) and her ET were all day 3. Neither of her now healthy children were good looking embies at all ( even at day3) so you womder if they would ever have made it if left to grow on. I guess I am coming now from a viewpoint where none of my 9 "good" embies made it to quality enough blasts to freeze so the whole "drop off" is really, really scary.
Praying you get at least 2 good ones so you have a spare ( or another sibling) on standby!

Lisa - my heart goes out to you. Sounds like a womderful service, very comforting I am sure

Sara and buliej - how are you hanging in there?

WTH - Get to it this w/e girl! Lets see a natral miracle before xmas!

Me - not much to report. Days dragging on and on as I count this last week down. DH is never that fussed by my symptoms etc after a cycle but this one has really got to him and he told me last night how desperae he was for this to work. We still haven't really discussed what to do if we get BFN. I think he likes the idea of doing PGD again but the costs understandably concern him.
I think I am really feeling the "pressure" of needing to get pg this time to get our PGD tested baby.

Sorry guys for being MIA - wrote a long email this morning but lost it.

Cuddlepie: The numbers look really good, will keep fingers crossed and think of you hoping your embies keep doing so well.

Sara

Good morning, girls. Could not get on BB at all yesterday afternoon so I guess that's why there's been no action here for a record 2 days!

Cuddlepie - thinking of you and hoping you get/got to transfer??????????? :pray:

Meredith - yep, that symptom analysing will definitely do your head in. Are you thinking of doing a HPT around the time of the BT? I just could not handle hearing it over the phone so chose to do one with DH when I knew the Pregnyl was well and truly out of my system but a test work work (15 dpo). I wanted to share the moment with DH - whether the outcome was joyous or sad. Just curious...

AFM - well, my spotting and cramping arrived right on cue, at midnight between Day 8 and 9m as it has since all non-PG cycles since Jan 2008. Quite light, and continued until after breakkie. Then returned for an hour again last night. But it has been heavier in the past on cycles where I have naturally fallen PG. I did spot for a couple of hours last month on Day 7 FSH, despite the fact my estrogen was well over 600. So maybe no harm done to my follies this month. Maybe the maca root and accupuncture have helped a little bit. I have spoken to two FS about this and neither will help or comment. They just say it won't happen on IVF (even though it does). My theory now is that around Day 8 or 9 the dominant follicle is trying to take over and perhaps the other follies stop producing as much E2. Only this does not explain why it still happens on an IVF cycle. Alternatively, maybe it is light because it has taken a few days for the lining to build only to be shed again.The more I think about it, the more it does my head in... :wall: End of my long-winded rant. I just don not know if this happening to anyone else and just wish my body would act more normally and continue to fear this is all pre-menopausal.

Hi,

Hope you're all fine, I wasn't able to access BB for the last two days. In the middle of a very stressful day at work, therefore only able to write a quick mail.

Cuddlepie: sending you a big :grouphug: was thinking of you and hoping that you're resting comfortably after transfer.

Meredith: hope you're okay, not long now till BT.

WTH, Buliej, Lisa, BW :hello:

Sara

Sorry not really up to personals today althoug I am hoping CP has had a sucessful transfer today.

Past 2 days I had beun to feel fairly confident i was actually pg. Usually i would have very strong AF cramps by now - not happening, plus I've had sore BBs and yesterday felt quite nauseus at times.
With all my other IUI cycles, this has always been a great sign and I have always done HPT around this time (12dpo). My "gut" feeling has always been right and if I think I am pg then have always been greeted with two strong lines.
Well, feeling confident, I did HPT today. NO second line. Not even a hint of a second line when I squinted!.
So I would have to say a defnite BFN for us and must be the whole IVF which is messing with my body. I know everyone will come in here and say "its to early" or "don't give up until your BT'" but i KNOW there is no chance. I have been pg 5 times and even though all but 1 were not sucessful, they all gave good strong BFP on HPT so a -ve HPT IS a BFN for me.
I am more shattered than i ever expeced to be. Had to call DH ome from work. I was sooooo hopeful for this cycle and just still in shock I guess. This year has just been bad news after bad news after bad news. I just don't know how much more I can take.
To add to that, I am stressing already about what we do next. DH thinks we should just go back to IUI and take our chances without PGD. He is worried not only b the costs, but also thinks all our embies were damaged by the testing. I can see his point given our "drop off" from 14embies and none frozen but I am also terrified of having more m/cs. Haven't got appt with FS until the end of Jan. I REALLY need some questions answered before then.
So sorry for the rant, I know everyone in here has faced failed cycles. I think I am just reaching the end of my tether at seeing our dreams slipping away faster by the day.

:comfort: Meredith, thinking of you and hoping against hope that just for once your gut feeling may be wrong... but I know it's awful having people build up false hope so I shall offer my support, my condolences and a comforting :hug: and the fervent hope that you do find answers very soon.

BW

Dear Meredith,

Still hoping that there is still a chance that the test is wrong but can understand how devasting it is.

Perhaps you could ring your FS and ask if they could slot you in earlier in case they have a cancellation or if you at least could talk to your FS over the phone. After my cancelled circle I was able to talk to the nurse about my options which also was of some help.

My FS also sometimes answer my questions via email, so maybe you could ask if that would be possible.

:grouphug:

Sara

Meredith, I am sorry to hear your news but really hope you are wrong. I know you don't want to hear this but until you have b/t please don't lose hope. I can totally understand 'reach the end of tether part', I was so feeling the same as you yesterday and had a big full on cry. I just feel I can't face this anymore...

Anyway, that cry must have helped me to face the TF day, I am feeling better. TF went well although we were an hour late due to so many scheduled in today at clinic.

Out of my 6 viable embies on Day 3, one is a front runner, a grade 2 blastcyst, 2 early blasties, the rest 3 are still in Day 3 cells-stage they said but they will keep an eye on them to see any more development. I am relieved about the result to say the least. Also happy to see improvement in the result that seems DH's improved SCSA result did make a difference from DAy3 to Day 5 development, normally we would see a huge drop off and most of them are fragmented.

FS suggested to transfer two, the grade 2 blastcyst and 1 early blasties, he said because we don't know whether in the next two days they will definitely be frozen, they are still perfect for transfer at this stage. The chance of multiple pregnancy is quite low and we don't want to waste a perfect embryo. So here I am with 2 on board now. We've never done 2 before I know it won't increase my chances but I am still excited. Hope they will grab on and stay for a long haul.

So very tired, got a bit back pain already, sorry no personals but a big hello to everyone! I will catch up on personals later...

Cuddlepie:

:stickyvibesgirl: :bluecheer: :leap: :cheer: :stickyvibesboy:

Lots of sticky vibes and a big hug, go the Christmas BFP!

Sara

Cuddlepie - I'm very excited for you...Also, I think 2 does increase your chances - my FS originally suggested transferring 2 to me...and we did the first time when we had 2 to transfer...for my next cycle if we don't do PGD I probably won't do 2 but if we do get to do PGD and end up with 2 good ones I most definitely would ask for both of them to be put in.

Oh how exciting CP - you better change your location to : IVF Island - lazing on a banana lounge watching Smith and Wouldloveabubba have ****tails

No ****tails for you my love