Hi Ladies. I have just started my first IVF cycle. I have fairly regular natural cycles with a short luteal phase but DH has a low sperm count with poor motility and so our assisted journey begins. I am now on day 3 of synarel and am supposed to go for a BT and scan next week to check whether my levels are supressed before commencing the purgeron(??sorry probably spelt that wrong) injections. Should I expect AF while on synarel?
My FS started me on CD22 and I would normally expect AF around CD31 which would be just about when they want me to come in for BT and scan to determine when to start the injections. I would have thought they wouldn't want to start stimulating my ovaries until I have had AF? They obviously know what they're doing but I don't
I'm no expert but I am currently in the middle of my first IVF cycle - had egg pick up yesterday so thankfully finished sniffing that dreadful stuff. Synarel won't affect your AF and they won't start you on Puregon injections until you get it, so don't worry. I assume the BT is just checking that Synarel is working and your natural hormones are being supressed - not sure why they are scanning you though. If you have any concerns, call your clinic or hopefully someone on BB has a bit more expert information to give you.
I wish you the very best of luck and hope your first cycle brings you your beautiful bundle of joy. Take care x
Thanks dd. I checked the plan my FS gave me and there is no scan so my bad. There is only a blood test so I guess they are just checking on the progress of Synarel as you said. Now I just want AF to arrive so I can start the Puregon injections!!! Never thought I'd be willing AF or injections to come but I can't wait to get the process well and truly underway.
How was the pick up? I hope they managed to get lots of good eggs that will produce top grade embryos for you. Wishing you the best of luck for your cycle. May the first cycle bring you what your heart desires. Please keep me updated. I'll be walking in your shadow so I am eager to hear more about your whole experience.
HI Jaxi, you will be on Synarel until your trigger injection so a few more weeks to go yet.
I hope you get AF soon, then we want the her to stay away for 9 months! I couldn't wait to start injecting! I felt I was doing something productive, rather than just sniffing that awful stuff. How do you find it? I used to gag every time that liquid hit the back of my throat - the taste is just vile. I found the injections a breeze though - not hard, and not painful - just many bruises on the tummy!
I stimulated too quickly on Puregon 150ml so they had to move my egg pick up date a few days earlier for fear I would over stimulate and have to cancel my cycle. I only had 7 injections when it's generally around 10-12. My scan last on Monday showed so many follicles that my clinic was so surprised I wasn't doubled over in pain. I had about 10 follicles over 18mm that day with about 20 around 13-15mm. There were also quite a few that were much smaller so not in the running. So because of these numbers and very high estrogen levels, they moved pick up to Wednesday when it should have been today. Stimulating too quickly meant most of the follicles just blew up but were not viable.
So, I had 13 eggs collected on Wednesday with 6 fertilised. I am praying so hard most of them make it to beautiful strong blasties and at this stage, transfer is on Monday.
I guess the first cycle is always going to be trial and error as they don't know how our bodies will react to the drugs. I am praying very hard that you are successful this cycle and hold your much longed for baby in just over 9 months time.
I would love to share this journey with you! Keep me posted on how you go hun x
Last edited by dusty; February 22nd, 2009 at 04:49 PM.
: not allowed to get around the automatic censor
dd thank you for sharing all of that with me. Your first cycle sounds like it's been a real success so far. 6 fertilised is a great start! I really really hope you get your beautiful strong blasties for your transfer on Monday. I will be thinking of you and keeping my fingers crossed for you.
I'm also due to start 150ml of Puregon once they give me the green light. I was worried it would be too low but maybe not! I have to keep reminding myself that the first cycle will be a bit of an experiment to see how my body responds. Can I ask - Do you suffer from PCOS? I was speaking to the nurse about my chance of being overstimulated and she said it would be unlikely with me as I don't have PCOS and am at a healthy weight. Apparently it's more of a concern for women with PCOS or those who are underweight. I'll be interested to see what the 150ml does for me.
I'm finding the synarel ok. It does leave a vile taste and yesterday I had this burning sensation in my nostril after using it for a good hour which was awful. I've also developed a bit of a sore throat and just generally feel blah and so lethargic. I'm on day 4 today so not sure whether I can attribute these to synarel or whether I have a bit of a bug!? I'm also drinking lots of water as I understand it helps with reducing chances of hyperstimulation and also helps with any side effects from the synarel. I feel like I'm running to the bathroom to pee every 20mins though!
So, the synarel spray it is for me for a while still. boohoooooo I'm SO impatient! Have my BT next Thur and I guess I'll know more from then. Will keep you updated and will be hanging to hear your progress after Monday. Wishing you the best of luck!!!!!!!!!
Hi ladies, just dropping in to say GL, and also confirm that yes, sometimes it is a bit of trial and error to get your FSH dose right, my first was 225 and I heavily over stimmed, cycle cancelled. Number 2 was 125, still over stimmed, but went to EPU but no ET. Third was at 75 but they had to up the dose after 8 days of stims and I ended up stimming for an extra 2 days on 100 FSH. My last cycle was FSH 100, this seems to be perfect for me. So yes, lots of trial and error for me.
Re my first EPU, my E2 levels were 22,000 on day of trigger, they retrieved 19 eggs, 15 fertilised, and froze them all. I did 3 x day 3 FETs with these. In hind sight if I could go back I would have grown them all to blastie and frozen the best. Because of the very high E2 levels, I believe that my embie quality was compromised, they were slow growing and moderately fragmented, the best day 3 embie I had was a 7 cell, the rest were all 5 or 6 cell at day 3, all with fragmentation.
Synarel - what to expect?
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