I just came out of my second IVF cycle with protocal of treating NK cell issue (Immune suppressive therapy). The protocal basically is the combination of prednisone and Clexane injection. Unfortunately this cycle failed again. My NK level is 30%, which I think is classified quite high. I only did a b/t not a biopsy and it was done May 2009.

The period started quite early, right on a week after two blastcysts were transferred (they were good quality - A grade, So Im trying to come to terms with what actually went wrong. ) and with quite a few clots in the first day or so then eased. I had symptoms like tight / swell tummy feel and digging sensation during a week after transfer but after DPO10 they all dissappeared. It feels like they are trying to implant but however some other force are still preventing them. When period starts, I also got some aches and pains in my left finger and legs, appearantly these are some symptoms when autoimmuane imbalance in your body but just not serious enough for clinical diagnosis (which I read in Alan Beer's book). So this also leads me to think my immune system somehow is still not in the clean for my embyros.

I thought there could be two possibilities, one is - my embyros are not strong eough, so they are just weed out after transfer. Well, nothing I can do about that, just need to play the numbers game then.

Second possibility, could it be the protocal is not effective enough to keep NK cell at bay and its still interferring with the implantation? Im on 20mg predinsone after EPU (before was 10mg from D1 of the cycle), what else can be done?

Murraycod, I read your treatment in the other thread about antibotics, what does it do? I might check with my FS about this.

Any one can offer any advice? Im going to see FS in a few weeks time to discuss this. Thanks!