Hi girls,
Am hoping I might get some insight into puregon and low response experiences. Last month I started a stim cycle and was put on Puregon (200 daily) and got 1 follie. On Day 9 the follie was 13mm, by EPU day it was 18mm. All indications were that it looked like a goodie as it had matured … but unfortunately it did not fertilise (via ICSI). Not sure how that happens given ICSI was used, Melb IVF does not offer any explanations either, other than there are many factors involved and it could be any number of them. Have gone back again this month and am on the same cycle, 200 daily dose of Puregon. Just had my Day 9 scan (am having scans on Day 9 as Day 8 fell on a Sunday on both occasions). Anyway, sure enough there is only 1 follie again, this time it is 10mm. Have been told to come back on Thurs for another scan and in the meantime still take the Puregon (200 daily) as well as Orgalutron daily for the next 4 days (which as some of you may know is $98 a pop with no form of rebate). So as you can see I truly am a low / poor responder to ovarian stim cycles (have tried gonal-f on higher doses last year … same sort of result). I’m turning 40 later in the year so don’t have time to waste and am getting a bit disillusioned with it all. Have been reading that some of you have had your cycles cancelled when you’ve only had 3 follies as this was seen as a poor result, so I’m not sure why they are still happy to proceed with my cycle when all I’m getting is 1 follie. Have also been thinking I may as well just do a natural cycle with ICSI as the medications don’t seem to be producing anything more than I normally would get. All up I have had 3 failed ICSI cycles so far and am now hoping this 4th one will produce better results … for no other reason but pure optimism. Would be interested in hearing from those of you that have had similar experiences … were you advised to proceed with a cycle with just 1 follie, was it successful? I know they say it takes just 1 egg … but realise that it also lowers my chances.