Anyone had success when diagnosed with NK Cells?

[blossom73]

Hi girls just wondering if anyone has had success with implantation and pregnancy after being diagnosed with NK Cells.
I have just had another transfer and BFN
I was diagnosed at beginning of feb with NK Cells i think in the 75th percentile which i think is quite high i actually have to call Dr Sacks to chat about results again next week.
I am hoping to hear some positive stories as right now i am starting to feel like i am fighting a uphill battle.
I was put on 30mg prednisone, 40mg clexane and 1 x cardiprin for treatment.
I am wondering how long it takes for the treatment to actually work and should i be on the prednisone all the time now untill we try again in 6 weeks?
Anyone used IVIG for treatment?
Would love to hear feedback.

[melbel]

I had ridiculously high levels of NK cells and now have aone year old playing in the next room.......so yes it can happen. I was on the same protocol as you prescribed by Dr Sacks but implemented by my FS here in Melbourne. I actually stayed on the prednisone between cycles at the level of 10mg after reading some research by Alan Beers and it was our second cycle that I fell and stayed pregnant. The book "Is my body baby friendly" by Dr. Alan Beers might be worth a read for you.
As for IVIG treatment I very much doubt you will be able to get approval to use it in this country as IVIG is a very very scarce and expensive treatment and you have togo before a panel to get approval for use...IVF is not an IVIG approved criteria in this country.

[trea]

Blossom

Yes, yes, yes. After years of infertility, failed IVF attempts, failed surrogacy attempts we found Dr Sacks. My uterine levels were fine but blood NK cells were elevated. I think 17% from memory. I asked Dr Sacks to be brutally honest about how many attempts it may take and he said 3. He was spot on. I was increased to 30mg pred and 40mg clexane and on our third go with him we got pregnant. I am typing this with my little girl Matilda on my shoulder. She was only born a few days ago and we are eternally grateful to Dr Sacks. Go for it and believe it will happen - he knows his stuff.

Good luck can't wait to hear some good news from you soon.

Trea (floating on cloud 9)

[mayaus]

Hello everyone,

I am new at this website, so hopefully this is the right way to post and comunicate ! Although I have a healthy daughter and had no problem at all at her pregnancy, when trying to a second child I have experienced several miscarriages I have had 6 pregnancy losses in the past year and a half and it have been really painful. Over that time, I have tried clexane 40 mg, aspirin ( cartia ), progesterone and even steroids and nothing worked. I was also diagnosed with high NK cells by Dr Sacks, but I am really concerned because talking to a friend from Brazil who have had 10 miscarriages, she could only carry to term after taking ivig ( immunoglobulin ) and the vaccines that Dt Alan Beer also applies. I did took these vaccines in Brazil, but kept loosing after that and they already expired ( they only last for 6 months ). So does any of you knows if it is possible to be treated with the ivig here in Sydney ? How about the immune therapy with the husband's leucocits ? Dr Sack's advise was to take the steroids ( 20 mg ) but because we are trying naturally, I can only take after I have a positive result, and by than it is already too late, since my bhcg levels are already coming down. Does any of you had success with the steroids ? When did you start taking it ? I am so desperate since I can't see a way out for my case right now... Thanks a lot !!!

[melbel]

My advice is to speak to Gavin about staying on a small dose of prednisone between cycles say 5 mg and then upping it on a positive pregnancy test...this is what we did.....you don't want to do it long term but for a few months should be okay...this is what we did to conceive our little one. there is a doc in Melbourne who uses not IVIG but intralipids therapy that may interest you as well...his name is Nick Lolatgis.

[mayaus]

Thank you so much for answering me Melbel. So did you finally carried to term only after taking prednisone ? What dosage were you at ? Do you remember what result you got for NK cells test ? Just wondering how bad mine is ( 16,9% ). I just can't understand why isn't the ivig used here in australia, since it is successfully used in so many other countries... Do you know about the lymphocyte immune therapy ? Is that available here ? Thanks a lot to all !